It will certainly be easier to emulate Windows on an Intel platform. I would expect to see hacks in both directions.
Dongles and hardware locks have been around for years to prevent software piracy. They work only to the extent that the programs they protect are used by people who can afford them and who need the support of the publisher. Anyone can download a hacked version of AutoCad.
Sorry PC people...but the New OS X TIGER eats anything and everything a PC has to offer for lunch....