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Stronger measures needed in Marburg Fever outbreak in Angola (from Doctors Without Borders)
Medecins Sans Frontieres ^ | April 18, 2005 | MSF staff

Posted on 04/19/2005 11:09:31 AM PDT by Judith Anne

A deadly and contagious Marburg Hemorrhagic Fever outbreak continues to ravage Angola. There is a high mortality rate of patients admitted to the isolation units - only two have survived more than 24 hours. Without a stronger response, the epidemic will continue to spread.

Marburg Fever continues to spread in the Angolan province of Uige. To date, the official deathtoll stands at 235, with 257 reported cases. Biological tests carried out by the WHO confirmed on March 22 the presence of the virus. Since then, 114 new cases have been identified, 107 of which have proved fatal.

Despite these alarming statistics, measures announced to contain the epidemic have been slow to act and have so far failed to stop the epidemic spreading. While the epicentre of the outbreak is in Uige, last week saw the emergence of new areas of infection. In Songo, an hour west of Uige, four cases have been reported. While in Negage, 30 minutes south-west of Uige, the figure stands at three. The health infrastructure in these two localities has been affected.

Fighting a deadly and contagious disease and a complex epidemic

Marburg Fever - from the same family as the Ebola virus - is a deadly and contagious disease. Stamping it out requires a rigorous, multi-level strategy.

Because Marburg Fever can be transmitted through direct contact with bodily fluids, it is imperative that isolation units be put in place to treat those affected. No specific treatment exists but measures must be taken to treat those affected (rehydration, administering of antalgics and drugs to prevent vomiting, etc.)

Since the beginning of the crisis our teams have set up two isolation and treatment units: one in Uige Hospital, and one in Amerigo Boavida Hospital in the capital, Luanda. 23 patients have already been admitted to the centre in Uige. Isolation units are also being set up in Negage and in Songo, while the unit in Camabatela is already in place.

Human and logistical action: Informing the population

To limit the risk of infection, efforts must be made to identify and assess suspected cases, and to locate and check on any people who may have come into contact with those affected by the virus. Nearly 500 'contacts' have so far been counted in Angola - 360 of these in Uige alone. In addition, strict sanitary procedures must be adhered to when burying victims of the Marburg virus - whether they have died at hospital or at home.

Such priorities require important logistic and human efforts. Protective clothing (gloves, gowns, masks, glasses, boots, etc.) is essential, while proper vehicles must be provided to locate suspected cases in different areas of the country, and to transport patients and bodies. All medical and non-medical personnel must be notified immediately.

Our volunteers are in charge of training Angolan medical and military personnel, alerting them to the strictest sanitary precautions to be taken in order to guarantee their own safety in the event of contact with victims and bodies. This effort must however be intensified.

If these measures are to succeed, they must be supported by specific policy aimed at informing the local population. So far little has been done to raise awareness, and in a climate of fear, MSF teams and WHO personnel have been met by hostile reactions during their visits to the areas of Cadongo and KimaKongo in Uige. Because fighting the outbreak means isolating patients and burying the victims in body bags, the local population often see the medical personnel as 'confiscating' the sick and the dead.

What is more, the high mortality rate of patients admitted to the isolation units (only two have survived more than 24 hours) has led to a culture of suspicion among the local population. Consequently, locals sometimes refuse to hand over the sick and the dead to medical teams, preferring instead to keep them at home, which creates a potential for future contamination.

By informing the population and alleviating the panic, those showing early signs of the virus may be hospitalised sooner - a move that will lead to a drop in mortality rates.

Reorganising the hospitals affected

Elsewhere, hospitals affected by the virus must completely reorganised to avoid any risk of the virus 'nosocomiale' infection (this occurs when the virus is spread in the confines of the hospital itself). All services must be disinfected and an isolation ward must be put in place.

Triage of patients must be stepped up in order to isolate suspected cases, and to prevent those infected by the virus coming into contact with patients of other illnesses.

These precautionary measures must be applied throughout the hospital. This involves not only the wearing of safety equipment but also the suspension of all invasive procedures (surgical operations, lab inspections, intravenous and intramuscular injections, etc.) with the exception live-saving operations (emergency surgery, caesarian sections, etc.) which should be carried out in accordance with strict sanitary procedures.

Inadequate reaction

For the time being, our efforts and those at both the national and international level remain largely inadequate given the gravity of the situation. It is imperative that Angolan authorities take into account the extent of the epidemic.

Without proper treatment of patients and protection of the population, Marburg Fever will continue to spread throughout Angola.


TOPICS: Foreign Affairs
KEYWORDS: africa; angola; health; marburg; outbreak
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Thanks to Dr. Niman for alerting me to this article.
1 posted on 04/19/2005 11:09:36 AM PDT by Judith Anne
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To: bitt; Dog Gone; Lessismore; Mother Abigail; EBH; 2ndreconmarine; djf; kanawa; Mr.Atos; PDT; ...

Okay, putting that ping list to work...


2 posted on 04/19/2005 11:11:22 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: kjenerette

...they should also take these kinds of measures with AIDS?


3 posted on 04/19/2005 11:14:27 AM PDT by Van Jenerette (Our Republic - If We Can Keep it!)
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Comment #4 Removed by Moderator

To: Van Jenerette

Goodness. We've alreaady had a post removed???


5 posted on 04/19/2005 11:24:54 AM PDT by null and void (RFID/0110 0110 0110 - It's all in the wristâ„¢...)
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To: null and void

I asked for it to be removed. I wasn't sure if I had permission to post comments from an email from Dr. Niman, and to be on the safe side, I asked it be taken off.


6 posted on 04/19/2005 11:26:34 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne

Amazing how little press this is really getting isn't it.


7 posted on 04/19/2005 11:30:01 AM PDT by Scythian
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To: Judith Anne
Stronger measures needed in Marburg Fever outbreak in Angola (from Doctors Without Borders)


In this case it would be DR. Obvious

8 posted on 04/19/2005 11:32:32 AM PDT by MD_Willington_1976
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To: Scythian

Probably, unless this gets out of Angola, we'll have to REALLY search for news.


9 posted on 04/19/2005 11:33:05 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne
Did Dr. Niman address why this outbreak is so much more deadly than previous Marburg outbreaks? In the past the mortality rate has been about 23%, with this one we are looking at less than 2% survivability rate.
10 posted on 04/19/2005 11:33:17 AM PDT by Sthitch
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To: MD_Willington_1976

ROFL! There is precious little to laugh about, with this disease--thanks! I feel so understood...;-D


11 posted on 04/19/2005 11:35:08 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne

This is really getting out of hand.........


12 posted on 04/19/2005 11:35:44 AM PDT by Gabz (My give-a-damn is busted.)
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To: Sthitch

Not to me, but you might find an answer in one of the radio interviews he's given. They are archived, and there are links at his web site.

I tend to think that like many bugs, Marburg has changed, or this is a different branch of the Marburg family we've never seen before.

For instance, Ebola has several different strains, one of which is airborne but does not cause disease in humans, although it's fatal to monkeys. Ebola Reston, I think it is.


13 posted on 04/19/2005 11:38:14 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Gabz
This is really getting out of hand.........

As long as it doesn't get out of Angola.......:-<

14 posted on 04/19/2005 11:41:39 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne

Thanks for the ping. Just pray that this monster bug burns itself out.


15 posted on 04/19/2005 11:42:28 AM PDT by dc-zoo
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To: dc-zoo

Yes.


16 posted on 04/19/2005 11:44:11 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne
Yes, Ebola Reston was the airborne strain. There has been some talk about using it as a vaccination for Ebola, but the last thing I heard was that it would be difficult to determine it efficacy, and safety so it is still under review.
17 posted on 04/19/2005 11:44:51 AM PDT by Sthitch
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To: Sthitch

Thanks for that information. I didn't know that, but as an idea it makes sense.


18 posted on 04/19/2005 11:46:23 AM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: Judith Anne

That is the key..........


19 posted on 04/19/2005 11:47:22 AM PDT by Gabz (My give-a-damn is busted.)
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To: Judith Anne
I'm not picking on you..LOL

It just seems that with such a devastating disease running rampant that there would be a lot more of a focus on it.

The problem is, and don't take me the wrong way I have a few friends from Africa & in Africa, that a lot of African countries see an outbreak like this as a way to grab some quick cash from industrialized nations (same is true with HIV & AIDS, it's an income source now from handouts), when they could just as easily quarantine the people, forcefully if need be (sad but in some cases the best way) and properly dispose of the bodies via cremation & also destroy any other carriers of the disease (animals etc)
20 posted on 04/19/2005 11:51:26 AM PDT by MD_Willington_1976
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