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Resistant starch could help combat leading cause of end-stage kidney failure
Medical Xpress / American Physiological Society / American Physiology Summit ^ | April 10, 2024 | Claudia Carrillo et al

Posted on 04/14/2024 10:07:52 PM PDT by ConservativeMind

Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study.

"Our study suggests that combining dietary interventions with a low dose of established medications for diabetic kidney disease management can provide a more feasible and lower side-effect alternative for patients to implement and improve their health outcomes by helping maintain their kidney integrity," said Claudia Carrillo.

Dietary-resistant starch is found in unripe bananas, cooked and cooled potatoes, legumes and whole grains. This type of carbohydrate ferments in the large intestine, where it feeds beneficial gut bacteria.

Carrillo's research team previously showed that giving rat models of type 1 and type 2 diabetes a diet high in resistant starch—where 35% to 50% of their carbohydrates were from resistant starch—prevented symptoms of declining kidney function.

"We wanted to explore a dietary intervention that was feasible to implement for diabetic patients in their daily lives," Carrillo said. "We opted to combine this dietary intervention at a lower dosage than before—equivalent to 5% to 10% of consumed carbohydrates from resistant starch—with low-dose renin-angiotensin system inhibitor, a blood pressure medication that had been shown to elicit the same effect on kidney health."

The researchers found that compared to the control groups, rat models of type 2 diabetes that consumed low-to-moderate amounts of resistant starch while also receiving blood pressure medication showed restored vitamin D blood levels and decreased loss of vitamin D and protein in the urine, which are symptoms of kidney deterioration seen during diabetes progression.

The study results also showed that the combined intervention imparted a protective effect on the kidney by modulating the renal renin-angiotensin system. This critical hormonal system helps regulate blood pressure and fluid balance in the body.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cooledpotatoes; fiber; kidney; kidneydisease; kidneyfailure; legumes; resistantstarch; unripebananas; vitamined; wholegrains
Just 5% of carb intake from resistant starch, along with a low dose renin-angiotensin inhibitor, save the kidneys.

Now, ACE-I and ARBs can act on this, in a way, but there are drugs that are actually called renin-angiotensin inhibitor that directly act on this pathway.

The study was not available for me to determine what, exactly, they used.

Regardless, the resistant starch appeared to work on the same pathway, so at least get your resistant starch in.

1 posted on 04/14/2024 10:07:52 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/14/2024 10:08:28 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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BKMRK.


3 posted on 04/15/2024 4:30:48 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: ConservativeMind

The myopia on display here is really quite pathetic. It really IS going to take them 50-100 years to figure out what some of us already know about the gut.

Don’t hold your breath for effective treatments for anything tangible...


4 posted on 04/15/2024 5:29:06 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: ConservativeMind

Once the Official Pedo of the Bidenskyyyyyyyy Administration is reelected, there will be no stopping his ass. We’re done.


5 posted on 04/15/2024 5:34:53 AM PDT by FlingWingFlyer (Gun show sales aren't the problem, public school zombie walkers are the problem.)
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To: FlingWingFlyer

Don’t know how this got here. Posted on the wrong post.


6 posted on 04/15/2024 5:39:54 AM PDT by FlingWingFlyer (Gun show sales aren't the problem, public school zombie walkers are the problem.)
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To: ConservativeMind
"Dietary-resistant starch is found in unripe bananas,..."

Kidney doctors will be aghast at this absurd statement...
Potassium & phosphorous are the two main enemies of diseased kidneys and ALL diets are designed to radically minimize the patient's consumption of both of these "killers"...

7 posted on 04/15/2024 10:45:04 AM PDT by SuperLuminal ( Where is Samuel Adams when we so desperately need him)
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To: SuperLuminal

I understand only kidney patients who have chronically high potassium levels are at risk from high potassium foods:

https://www.thekidneydietitian.org/potassium/


8 posted on 04/15/2024 7:29:34 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

No...

Anyone with chronic kidney disease MUST avoid potassium,, phosphorous, sodium, and large amounts of protein...

Otherwise, death is just a few steps away...


9 posted on 04/15/2024 7:39:13 PM PDT by SuperLuminal ( Where is Samuel Adams when we so desperately need him)
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