Posted on 10/19/2023 9:22:53 PM PDT by ConservativeMind
About 800 million children have blood lead levels that affect their brain.
Guilarte has been among the first to document what's happening at the cellular level of the brain that triggers a cascade of lifelong consequences—from learning difficulties and lower IQ scores to the risk of psychiatric diseases and drug abuse in adulthood.
Can the damage lead has done to their children ever be undone?
Decades of research has brought Guilarte and his collaborators closer to an answer. They've identified a certain flavonoid, a class of nutrients present in fruits and vegetables, that reverses some of the negative effects of lead and could be a possible therapeutic solution.
Guilarte found lead acts as the silencer by interfering with a unique protein receptor known as the N-methyl-D-asparate receptor (NMDAR).
NMDAR binds metals, like calcium and zinc, to operate. Lead acts as an imposter, preventing it from functioning properly.
A glimpse below the "iceberg" revealed why. During brain development, activation of the NMDAR produces a peptide—brain-derived neurotrophic factor (BDNF)—that's essentially "food for the brain." Guilarte's team added BDNF to lead-impaired neurons in culture from the hippocampus, a brain region important for learning and memory, and it was able to reverse the detrimental effects of lead on the ability of neurons to communicate. But BDNF can't be put into a pill. It would break down in the stomach before ever crossing the blood-brain barrier.
Guilarte and colleagues identified a promising alternative—the flavonoid 7,8-dihydroxyflavone—an effective molecule currently available as a supplement and capable of reaching the brain. In the lab, it successfully came to the rescue in lead-exposed animals, reversing some of lead's damaging effects.
A move forward, this discovery was further proof that negative effects of lead exposure on the brain could be reversed and possibly holds the key to treating lead-exposed children.
(Excerpt) Read more at medicalxpress.com ...
And how many of us when children suffered the practice of opportunistic dental practices?
Too bad Nero couldn’t get a hold of this to put in his wine...
Oh no! That would diminish the sinister and farcical gossipy aspects of Roman history that we so much enjoy — and possibly have us still speaking Latin.
My guess is that 799 million of them don’t live in the US.
What foods is it found in?
I’ll bet they are not crimping lead sinkers onto their fish line.
And they are not seeking gut piles to consume.
So just where are they getting it, from the air?
And who is pumping out lead filled air?
(What is the Chinese symbol for Lead?)
"Tropoflavin, also known as 7,8-dihydroxyflavone, is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves."
"Tridax procumbens, commonly known as coatbuttons[2] or tridax daisy, is a species of flowering plant in the family Asteraceae. It is best known as a widespread weed and pest plant."
"Primula (/ˈprɪmjʊlə/)[1] is a genus of herbaceous[2] flowering plants in the family Primulaceae. They include the primrose (P. vulgaris), a familiar wildflower of banks and verges. Other common species are P. auricula (auricula), P. veris (cowslip), and P. elatior (oxlip). These species and many others are valued for their ornamental flowers. They have been extensively cultivated and hybridised (in the case of the primrose, for many hundreds of years). Primula are native to the temperate Northern Hemisphere, south into tropical mountains in Ethiopia, Indonesia, and New Guinea, and in temperate southern South America. Almost half of the known species are from the Himalayas."[2]
Godmania aesculifolia is a species of flowering plant in the family Bignoniaceae, native to the New World tropics.[2][3][4] A tree, it contains 7,8-dihydroxyflavone, a flavonoid.[5]
https://nootropicsdepot.com/7-8-dihydroxyflavone-capsules/
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