Free Republic
Browse · Search
General/Chat
Topics · Post Article

To: SeekAndFind

Look up Amlodipine vs. Covid19. There is a Chinese study that says people with high blood pressure that are on Amlodipine kick the disease with ease. I can attest to it personally.


2 posted on 06/20/2020 7:57:12 PM PDT by Paddy Irish
[ Post Reply | Private Reply | To 1 | View Replies ]


To: Paddy Irish

I pray the virus dissipates into oblivion and to God alone be the glory!


3 posted on 06/20/2020 8:00:26 PM PDT by CondoleezzaProtege
[ Post Reply | Private Reply | To 2 | View Replies ]

To: Paddy Irish

Not Chinese study, may be related.

- - - - - - - - - - - - - - - - - -

Nifedipine and Amlodipine Are Associated With Improved Mortality and Decreased Risk for Intubation and Mechanical Ventilation in Elderly Patients Hospitalized for COVID-19
Isaac Solaimanzadeh 1
Affiliations

PMID: 32411566 PMCID: PMC7219014 DOI: 10.7759/cureus.8069

Free PMC article
Abstract

Dihydropyridine calcium channel blockers (CCB) are typically used agents in the clinical management of hypertension. Yet, they have also been utilized in the treatment of various pulmonary disorders with vasoconstriction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been implicated in the development of vasoconstrictive, proinflammatory, and pro-oxidative effects. A retrospective review was conducted on CCB use in hospitalized patients in search of any difference in outcomes related to specific endpoints: survival to discharge and progression of disease leading to intubation and mechanical ventilation. The electronic medical records for all patients that tested positive for SARS-CoV-2 that were at or above the age of 65 and that expired or survived to discharge from a community hospital in Brooklyn, NY, between the start of the public health crisis due to the viral disease up until April 13, 2020, were included. Of the 77 patients that were identified, 18 survived until discharge and 59 expired. Seven patients from the expired group were excluded since they died within one day of presentation to the hospital. Five patients were excluded from the expired group since their age was above that of the eldest patient in the survival group (89 years old). With 65 patients left, 24 were found to have been administered either amlodipine or nifedipine (CCB group) and 41 were not (No-CCB group). Patients treated with a CCB were significantly more likely to survive than those not treated with a CCB: 12 (50%) survived and 12 expired in the CCB group vs. six (14.6%) that survived and 35 (85.4%) that expired in the No-CCB treatment group (P<.01; p=0.0036). CCB patients were also significantly less likely to undergo intubation and mechanical ventilation. Only one patient (4.2%) was intubated in the CCB group whereas 16 (39.0%) were intubated in the No-CCB treatment group (P<.01; p=0.0026). Nifedipine and amlodipine were found to be associated with significantly improved mortality and a decreased risk for intubation and mechanical ventilation in elderly patients hospitalized with COVID-19. Further clinical studies are warranted. Including either nifedipine or amlodipine in medication regimens for elderly patients with hypertension hospitalized for COVID-19 may be considered.

Keywords: amlodipine; calcium channel blockers; coronavirus disease (covid-19); covid-2019; high altitude pulmonary edema; hypoxia; nifedipine; pulmonary artery hypertension; pulmonary vasoconstriction; pulmonary vasodilation.

Copyright © 2020, Solaimanzadeh et al.
Conflict of interest statement

The authors have declared that no competing interests exist.
Figures

https://pubmed.ncbi.nlm.nih.gov/32411566/


5 posted on 06/20/2020 8:08:27 PM PDT by Norski
[ Post Reply | Private Reply | To 2 | View Replies ]

To: Paddy Irish

Paddy Irish wrote:

“Look up Amlodipine vs. Covid19. There is a Chinese study that says people with high blood pressure that are on Amlodipine kick the disease with ease. I can attest to it personally.”

You take amlodipine regularly, then at some point you caught the virus, and was able to give it the boot?


6 posted on 06/20/2020 8:09:41 PM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000)
[ Post Reply | Private Reply | To 2 | View Replies ]

To: Paddy Irish

I take Amlodipine daily, a small dosage. Add this info to my type O neg blood and the vitamin C & D I also take and I’m feeling pretty good.


13 posted on 06/20/2020 10:20:25 PM PDT by citizen (Women are from Venus and Men are from Mars. A,ll the other genders you make up are from Uranus.)
[ Post Reply | Private Reply | To 2 | View Replies ]

Free Republic
Browse · Search
General/Chat
Topics · Post Article


FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson