Dosing Strategy PDF:
https://www.evms.edu/uploads/magazine/9-4/downloads/Dosing_strategy.pdf
1 | Page Vitamin C, Hydrocortisone and Thiamine For the treatment of Severe Sepsis and Septic ShockVitamin C, Hydrocortisone and Thiamine dosing protocol
Vitamin C: 1.5 g IV q 6 hourly for 4 days or until discharge from the ICU.
Hydrocortisone: 50mg IV q 6 hourly for 4 days or until discharge from the ICU. Taper is not required.
Thiamine: 200mg IV q 12 hourly for 4 days or until discharge from the ICU.
Alternative dosing: 100mg IV q 6 hourly for 4 days. Vitamin C: Vitamin C is provided by the manufacturer as a 50 ml vial at a concentration of 500mg/ml.
Three (3) ml of vitamin C will be placed in a 100ml bag of either dextrose 5% in water (D5W) or normal saline and infused over 30-60 minutes. The Vitamin C min-bag solution is stable for in excess of 24 hours (should be protected from light).
Hydrocortisone:Hydrocortisone 50 mg bolus q 6 hourly
Thiamine: Intravenous thiamine (200 mg) is placed in a piggyback in 50 ml of either D5W or normal saline and administered as a 30-minute infusion.
NOTE: The Vitamin C and Thiamine can both be mixed in the same mini-ba
This regimen can be made up and used at any hospital from a large one to a 4 bed unit.
If it works, it will be obvious with the results.
No big drug company will make tons of money and billions of $’s will not be spent on double blind bs studies at NIH or CDC.