The 1916 Cumberland vs. Georgia Tech football game was the most lopsided in the history of college football, with Georgia Tech winning 2220
The 2001 GMAC Bowl.
Don’t laugh. Look at the score, point swings, individual and team records, etc.
It was absolutely wild - especially the 4th quarter. One of the best ones ever. Go to youtube and watch the videos of it.
https://en.wikipedia.org/wiki/2001_GMAC_Bowl
Cumberland University is only a couple of miles from my home.