Diphenhydramine (Benedryl), doxepin, mirtazapine: three of the worst and I’ve been on all three but only for short time periods, fortunately. If possible, you want to be on substitutes that DO NOT CTOSS the blood-brain barrier.
CROSS
I used to use benedryl for allergy attacks...hated it...now take a mega dose of vitamin C and am finding it works!