The active agent in Jimsonweed is atropine which has been used in traditional medicine and recreational abuse over centuries.
The leaves are generally smoked either in a cigarette or a pipe. During the late 18th century, James Anderson, the English Physician General of the East India Company, learned of the practice and popularized it in Europe.
The Zuni people once used datura as an analgesic to render patients unconscious while broken bones were set.
The Chinese also used it as a form of anesthesia during surgery.
An individual seed contains about 0.1 mg of atropine, and the approximate fatal dose for adult humans is >10 mg atropine or >2–4 mg scopolamine.
Jimsonweed intoxication typically produces delirium, hallucination, hyperthermia, tachycardia, bizarre behavior, urinary retention, and severe mydriasis with resultant painful photophobia that can last several days.
Pronounced amnesia is another commonly reported effect. The onset of symptoms generally occurs around 30 to 60 minutes after ingesting the herb. These symptoms generally last from 24 to 48 hours, but have been reported in some cases to last as long as 2 weeks.
Smoke it with 2 PAM Chloride if you’re going to downtown El Lay!
“Mad as a hatter, blind as a bat, red as a beet, hot as a hare, and dry as a bone”
(We could use another episode of “Tales from the ER”, just sayin’...)