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Infant Exposure to Maternal Depression Affects Later Brain Development, Study Shows
American Psychiatric Association ^ | May 6, 2019 | Ende, Vurlhurst, et al

Posted on 05/07/2019 10:49:26 PM PDT by tired&retired

Exposure to maternal depression during the first months of life may have a lasting negative impact on brain development, suggests a study published Monday in AJP in Advance.

“These findings suggest that the perinatal period, particularly the postnatal period, may be critical for prevention of maternal depressive symptoms in view of the long-term association with child brain development,” wrote Runyu Zou, B.Med., M.P.H., of Erasmus Medical College, the Netherlands, and colleagues.


TOPICS: Health/Medicine
KEYWORDS: depression
The single-time-point analyses showed that maternal depressive symptoms at child age 2 months were associated with smaller total gray matter volume and lower global fractional anisotropy (FA), whereas maternal depressive symptoms assessed prenatally or in childhood were not. The trajectory analyses suggested in particular that children exposed to persistently high levels of maternal depressive symptoms across the perinatal period had smaller gray and white matter volumes as well as alterations (i.e., lower FA) in white matter microstructure compared with nonexposed children. Furthermore, the gray matter volume differences mediated the association between postnatal maternal depressive symptoms and child attention problems.
1 posted on 05/07/2019 10:49:26 PM PDT by tired&retired
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To: tired&retired

This relates to Attachment Syndrome issues.


2 posted on 05/07/2019 10:50:37 PM PDT by tired&retired (Blessings)
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To: tired&retired
A lot of what has been attributed to genetics is actually determined at the epigenetic level, and emotional attachment and nurturing can most definitely affect epigenetic programming - independent of actual genetics.

“Some seed falls on the path (wayside) with no soil, some on rocky ground with little soil, and some on soil which contained thorns. In these cases the seed is taken away or fails to produce a crop, but when it falls on good soil it grows, yielding thirty, sixty, or a hundredfold.”

Parenting and nurturing matter, a ton.

3 posted on 05/07/2019 10:59:21 PM PDT by neverevergiveup
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To: neverevergiveup
A lot of what has been attributed to genetics is actually determined at the epigenetic level, and emotional attachment and nurturing can most definitely affect epigenetic programming - independent of actual genetics.

Yes. I was thinking the same, but hard to sort out the effects.

4 posted on 05/07/2019 11:23:20 PM PDT by marktwain (President Trump and his supporters are the Resistance. His opponents are the Reactionaries.)
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To: tired&retired

“May have.”
“Suggests.”


5 posted on 05/08/2019 3:07:03 AM PDT by Tax-chick ("The villain is not the market but the state." ~ Jonah Goldberg)
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To: Tax-chick
It's called Grant Money.

My kids never knew I was depressed. Hell, I didn't even know.

6 posted on 05/08/2019 3:15:37 AM PDT by Sacajaweau
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To: marktwain; neverevergiveup
Plausibly, the development of the gut biome in infancy may be one mechanism involved. It seems that certain bacteria produce a substance that mimics a dopamine metabolite.

Gut bacteria might influence depression, and this is how

7 posted on 05/08/2019 4:32:19 AM PDT by Rockingham
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To: marktwain

My research shows that the greatest influence on a child’s personality development is the period in their mother’s womb. A child in the womb can’t differentiate between their mother’s experiences and emotions and their own.


8 posted on 05/08/2019 4:36:06 AM PDT by tired&retired (Blessings)
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To: Rockingham

The influence of gut biome is that great gut flora is often referred to as psychobiotics in psychiastry.

For example, 95% of the 5Htp, the precursor to serotonin is produced in the enterochromaffin like cells in the lining of the upper gastrointestinal tract. This is the “feel good” chemistry as it suppresses negative emotions from surfacing and is the reason for Prozac and other SSRI’s.

While the molecule is too big to cross the blood brain barrier under normal circumstances, stress causes the blood brain barrier to become super permeable.


9 posted on 05/08/2019 4:44:56 AM PDT by tired&retired (Blessings)
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To: Sacajaweau

There are so many “may have,” “suggests,” and other weasel-words in practically every report of a “scientific” “study.” We might as well all go out and play in traffic for all “scientists” know.


10 posted on 05/08/2019 4:52:05 AM PDT by Tax-chick ("The villain is not the market but the state." ~ Jonah Goldberg)
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To: tired&retired
I wonder if an aspect of maternal depression is that moms don't take enough time being traditional moms and home makers. Time devoted to family and home, away from other pressures such as work for the mom and too much, too early socialization for the infant are what I'm wondering about. Could this increase the chances for depression in the mom and negatively impact the physical and mental growth of the child?

That would be an interesting study. Compare how infants develop in various environments. The way this article reads, it could lead to a conclusion that moms need mind-altering meds to cope.

11 posted on 05/08/2019 4:53:27 AM PDT by grania ("We're all just pawns in their game")
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To: Tax-chick
I was too busy and too tired to be depressed. Babies are just a joy....even the ones that scream and cry. I had three in 4 years. They're in their 50's now.

That little phrase...You're a mother forever....so true.

My 55 year old daughter still calls me when the weather is bad to say she arrived safely.

12 posted on 05/08/2019 5:00:32 AM PDT by Sacajaweau
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To: grania

Many potential factots.

Hormone imbalances...

Stress of being a good mother and working..

Single parenting

Bad relationships


13 posted on 05/08/2019 6:54:05 AM PDT by tired&retired (Blessings)
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