Posted on 06/29/2018 7:45:13 PM PDT by ConservativeMind
Liver cancer is one of the most frequent cancers in the world, and with the worst prognosis...The most aggressive and frequent form of liver cancer is hepato-cellular carcinoma (HCC); little is known about it and there are relatively few treatment options.
Researchers from the Spanish National Cancer Research Centre (CNIO), have produced the first mouse model that faithfully reproduces the steps of human HCC development, from the appearance of the first lesions in the liver to the development of metastasis. The results, published in the prestigious journal Cancer Cell, indicate that diets rich in nicotinamide riboside, a derivative of vitamin B3, protect these mice from developing HCC in its most initial stage, when genotoxic stress is damaging cellular DNA. They also show a curative effect of the diet in those mice that had previously developed the disease.
The inverse relationship between NAD+ and cancer awakened the curiosity of the researchers: could an increase in NAD+ have beneficial effects on the disease? When the scientists supplemented the diet in genetically modified mice with nicotinamide riboside, a derivative of vitamin B3 that increases intracellular levels of NAD+, they did not observe tumour development. Surprisingly, when they gave this diet to mice that had already developed the disease, the size of the tumours was reduced and they eventually disappeared.
The results have been reproduced in other types of cancer such as pancreatic cancer.
(Excerpt) Read more at medicalxpress.com ...
This substance, “nicotinamide riboside,” is readily available on Amazon, and we just started taking this three weeks ago.
We will inform him of this potential option to share with his doctor.
It seemed to reverse this form of liver cancer and pancreatic cancer, but both in mice, only.
Not just goodfor cancer.
Indeed. My wife and I are trialling it to see if start to feel a bit “younger.”
There are several other supplements along these lines we are trying. They surround helping mitochondria and reducing Advanced Glycation End products (AGE).
It may work in humans too.
Nothing us certain, but I believe in trying things, especially when things are serious and there aren’t many or any good alternatives.
Good luck. I hope it works.
Perhaps, but lots of things cause (and cure) cancer in mice.
What strength is recommended?
Mind mentioning the other supplements you are trying other than NAD+?
Great news for mice.
I have not read the equivalents for people.
My wife and I are taking 150 mg a day, but the bottle says people can take 600 mg every day.
It is a B vitamin relative, so we generally excrete what we don’t need, but it also means we can’t make it, either.
After my mom died from pancreatic cancer, I saw a Vitamin D article about the benefits of Vit. D and cancer. I’ve taken it religiously every day since. Guess I’ll be taking the Vit B3 now as well. I’m confused how it is different from Niacinimide, which I have 3 new bottles of for my dog’s SLO. Interesting.
We are also now taking:
- PQQ (20 mg)
- MitoQ (20 mg)
- Riboflavin-5-Phosphate (50 mg)
- Pyridoxal 5’-Phosphate (100 mg)
- L-Carnosine (500 mg)
These are in addition to Ubiquinol (100 mg) which we already had. We take other items, but these are the new ones.
On the MitoQ, we are taking 10 mg a day—not 20 mg.
I suspect many of the (mice) cancer cures don't work in humans because the FDA requires humans to undergo chemo first.
coq10 one of them?
Thanks much.
It helps allow the MitoQ to go where it’s needed most—deep into the mitochondria where normal CoQ10 or ubiquinol rarely gets. MitoQ specifically targets where it is most needed 700-1000X more than the other two.
Prayers for your bother in law...
Thank you from both my wife and myself.
The big three for a long time have been: ALC, ALA, CoQ10.
Have you tried Carnosine?
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