Posted on 06/23/2018 8:15:47 PM PDT by ConservativeMind
Ironic that you mention “puzzle”; I write about that metaphor at length.
Here’s a new piece, absent missing content from your comment:
Depression is caused by hormonal imbalance (my own theory, particularly-given my health recovery and its positive effects, including reversing all symptoms of depression et al). Systemic hormonal imbalance, when unchecked, is like cocking the gun at the temple. The problem is that the shot never comes; it’s a slow, painful demise in many cases.
I don’t agree with the B12 shots for depression. Your comment on “symptom of a greater undiagnosed problem” is very prescient.
The problem is that waiting until cancer expresses is too late, but humans respond better to crises than evidence...
And I am calling it out as BS.
Are you seriously going to go “peer-reviewed journal” on me?
I might not be able to contain my laughter...
I’ve discovered several unique attributes relating to cancer patients not identified in the research journals that lead me to believe that the predisposition to cancer originates in an immune system suppression caused by the allosteric enzymes in the liver inhibiting the detox process rather than facilitating it. So that enzymes, such as the cytochrome P450 group which actually creates the half life of most prescription medicines by detoxing them from the body are not available for the normal detox process.
This overload on the liver detox system is especially true in the elderly who take a lot of prescriptions and have a lower liver detox response.
bookmark
Baking soda is communist. Arm and Hammer baking soda still has the glaring red seal. Over a century of supporting the Left.
There are many types of depression, or causes, both biochemically and psychologically.
For example for women with severe PMS and/or post partum there is a copper toxicity depression that only happens when certain hormones are out of balance.
This is why genotyping is such a fabulous medical screening diagnostic tool as it determines which type of depression a person is more likely to have and which treatment and dose would most likely be best/ This all from looking at DNA.
I’ve pulled the referenced research article and will read it, as I do many. While the Science Daily articles are good, they are just a quick summary.
Too many variables are left unconsidered in most research and the normal research trick is to create sample bias in specific attributes of the general population and then try to extrapolate it back over the entire population.
“Are you seriously going to go “peer-reviewed journal” on me?”
It seems that all you offer is ridicule.
That may have rhetorical value, but not logical or scientific value.
I was at Harvard years ago when Herb Benson presented his huge study using Carmelite Nuns to pray for cancer patients. The results after spending hundreds of thousands of dollars were INCONCLUSIVE.
I laughed at him and explained of course they would be...
In 100% of my tests with people with cancer I have identified a reversal of the emotional subconscious reward punishment system creating a self punishment through the immune system. Bottom line, most people with cancer are good people. Mean nasty pricks tend to not get cancer. There are many variables, but this one I have found 100% of the time without exception, in all types of cancer.
If you have a person with cancer due to this reversal, the prayer, or positive stimulus is viewed as a negative stimulus by the cancer patient. Thus in many the prayer would result in the reverse of the expected result.
I’m currently working on a research paper to present at a medical school in early 2019 on the neuroscience of prayer that explains this.
PS.. I have found this same attribute in MS and ALS.
I made popcorn, but can’t eat it until I cease my belly roll.
“Climate change” proclaimed the same, so stick this in your hat:
https://www.ncbi.nlm.nih.gov/pubmed/20458086
This is one of dozens of studies linking impaired health with use of PPIs. Thus, any “therapy” which increases gastric pH has a risk factor of significance, not of any benefit whatsoever. I don’t care if it’s homeopathic or pharmacological: It’s DUMB to increase gastric pH artificially for ANY reason.
I’m ignoring further comments from you; I feel like I’m exchanging words with a prog and it’s interfering with my laughter euphoria.
There are many P450 enzymes. If I remember correctly the main one for the majority of prescription half life creation is CYP3A4.
Here is the meat of the journal article:
Published today in the journal Cell, the study details how in response to acidity cells turn off a critical molecular switch known as mTORC1 that, in ordinary conditions, gauges the availability of nutrients before giving cells the green light to grow and divide. That event, Dang and his colleagues show, shuts down the cell’s production of proteins, disrupting their metabolic activity and circadian clocks, and pushing them into a quiescent state. They also demonstrate that this acid-mediated effect might be relatively easy to reverse — a finding that could help improve a variety of cancer therapies.
“In tumors grafted into mice, we see mTOR activity in spotty places where there’s oxygen,” says Dang who is also a professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute. “But if you add baking soda to the drinking water given to those mice, the entire tumor lights up with mTOR activity. The prediction would be that by reawakening these cells, you could make the tumor far more sensitive to therapy.”
The researchers show that in acidic conditions protein motors propel lysosomes carrying mTOR away from the area around the nucleus, where they’re ordinarily located. This separates mTOR from a protein required for its activation, RHEB, which continues to hang around at that location. Lacking one of its key activation signals, mTOR remains dormant, suspending the synthesis of proteins — including the components of the cell’s molecular clock — along with most metabolic activity.
“Cells don’t want to make proteins or other biomolecules when they’re under stress,” says Dang. “They want to slow things down and only awaken when things return to normal.”
The researchers show that baking soda can reverse this effect. When given to mice in their drinking water, it surprisingly sufficed to neutralize the acidity of hypoxic patches in tumors. This sent lysosomes zipping back to the nuclear periphery in cells — where RHEB was waiting — and restored the activity of mTOR.
All this is relevant to cancer because researchers have long known that quiescent cells cannot typically be killed by chemotherapy. Notably, Dang and his team also found that T cell activation, which is essential to most immunotherapies, is similarly compromised under acidic conditions.
“We started out with a question about oxygen starvation and the circadian clock, and we ended up discovering a new mechanism by which acidic conditions in tissues shut off a lot of things — including the cell’s molecular clock,” muses Dang.
You are going to ignore me after you make stupid comments to me?
That’s rich!
The whole subject of oxygen availability, hypoxia and cancer fascinates me. Currently they are using injections of drugs like Avastin, an anti VEGF or anti vascular endothelial growth factor to restrict capillary growth, thus restricting nutrients and oxygen to the growing tumor.
Avastin was originally used as an injection in the eye to inhibit the capillary growth leading to wet macular degeneration.
Baking soda is not a Proton Pump Inhibitor (PPI), and does not inhibit the production of gastric acid. It neutralizes acid on contact, but does not impede the natural process of regulation or production.
So your confusion of those situations with this one is telling.
No, choosing to be ignorant and acting like a progressive...
THAT’s rich. I gave you the resource to expound your knowledge and reverse said ignorance; your choice.
Looking forward to reading further commentary from you in the morning on this; I can always use help with my daily deuce.
Good ignoring example of me, liar!
Conflation is a sign of conflict & bias. What is your bias here?
PPIs have the effect of increasing gastric pH.
Sodium bicarbonate has the effect of increasing gastric ph.
Please cite your own confusion, as I have none on the effects thereof.
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