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What is urea cycle disorder?

Urea cycle disorder is a genetic disorder that prevents the body from removing ammonia from the blood stream.

Ammonia is a toxic substance that causes irreversible brain damage or death when it reaches the brain.

Metabolic stressors, including high protein intake, excessive exercising and dieting, can create excessive ammonia in the body.

The disorder is caused by a mutation of one of the six enzymes responsible for the urea cycle.

These enzymes are responsible for removing ammonia from the blood stream.

The urea cycle involves a series of biochemical steps in which nitrogen, a waste product of protein breakdown in the body, is removed from the blood and converted to a compound called urea.

Normally, the urea is transferred into the urine and removed from the body.

In urea cycle disorders, the nitrogen accumulates in the form of ammonia, a highly toxic substance, resulting in elevated blood ammonia.

1 posted on 12/12/2017 2:30:36 PM PST by Red Badger
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To: Red Badger

With that disease, how did she survive until 25?


2 posted on 12/12/2017 2:33:27 PM PST by PGR88
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To: Red Badger

“Meegan’s death certificate lists “intake of bodybuilding supplements” “

IOW, a needle was used and she was stacking 10 different varieties of bull test, HGH, etc.


4 posted on 12/12/2017 2:37:53 PM PST by Electric Graffiti (Obama voters killed America...Treat them accordingly.)
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To: Red Badger

she should have dined with Trump occasionally.


6 posted on 12/12/2017 2:38:31 PM PST by Pollard (TRUMP 2020)
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To: Red Badger

How many grams of protean was she taking in daily? The max should be no more than 60grams in any form.


7 posted on 12/12/2017 2:39:25 PM PST by SkyDancer ( ~ Just Consider Me A Random Fact Generator ~)
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To: Red Badger

Next time someone tells me they were bedridden with double ammonia I’ll take them seriously.


9 posted on 12/12/2017 2:41:48 PM PST by stormhill
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To: Red Badger

I prefer my protein from a nice juicy rare steak.


12 posted on 12/12/2017 2:45:25 PM PST by Lurkina.n.Learnin (Wisdom and education are different things. Don't confuse them.)
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To: Red Badger

You know the old joke... The unhealthiest people at a bodybuilding contest are the ones up on stage.


16 posted on 12/12/2017 3:02:23 PM PST by Wolfie
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To: Red Badger
Ms White said: “I couldn’t believe what the doctors were telling me, she was dying. “I said, ‘You have to give her more time’,

like it was up to the Doctor...

20 posted on 12/12/2017 3:13:04 PM PST by Chode (You have all of the resources you are going to have. Abandon your illusions and plan accordingly.)
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To: Red Badger
Meegan, competed in body building competitions

Hold on now. That killed her right there. Competing in competitions is deadly. Extremism kills.

The Extremily Extreme Extremist here, would have to agree.

Two of my relatives are dying from running competitions.

26 posted on 12/12/2017 3:35:44 PM PST by TheNext (DACA is INVASION!)
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To: Red Badger

RIP.


28 posted on 12/12/2017 3:38:33 PM PST by fieldmarshaldj ("It's Slappin' Time !")
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To: Red Badger

Interesting. There was an article posted on FR yesterday about a link between Urea buildup and dementia.


29 posted on 12/12/2017 3:50:39 PM PST by IamConservative (Suppose you were an idiot. And suppose you were a member of Congress. But I repeat myself.)
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To: Red Badger

You’ll live longer if you consume a breakfast of black coffee and cigarettes.


33 posted on 12/12/2017 4:00:34 PM PST by vigilante2 (I fixed my flag)
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To: Red Badger

Condolences to family and friends of Meegan Hefford.


46 posted on 12/12/2017 4:46:20 PM PST by PGalt
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To: Red Badger

Wife and I watched a Chicago Med with a similar case except the patient was a vegan with that abnormality. She restricted her diet so much, her body began feeding on her own muscle...digesting the protein and releasing ammonia which eventually led to her brain death.

First I’ve ever heard of that situation.


49 posted on 12/12/2017 6:58:40 PM PST by moovova
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