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Antibiotic-resistant microbes date back to 450 million years ago, well before the age of dinosaurs
phys.org ^ | 05/11/2017

Posted on 05/14/2017 8:00:08 AM PDT by BenLurkin

[E]nterococci, including those that have never been found in hospitals, were naturally resistant to dryness, starvation, disinfectants and many antibiotics. Because enterococci normally live in the intestines of most (if not all) land animals, it seemed likely that they were also in the intestines of land animals that are now extinct, including dinosaurs and the first millipede-like organisms to crawl onto land. Comparison of the genomes of these bacteria provided evidence that this was indeed the case. In fact, the research team found that new species of enterococci appeared whenever new types of animals appeared. This includes when new types of animals arose right after they first crawled onto land, and when new types of animals arose right after mass extinctions, especially the greatest mass extinction, the End Permian Extinction (251 million years ago).

From sea animals, like fish, intestinal microbes are excreted into the ocean, which usually contains about 5,000 mostly harmless bacteria per drop of water. They sink to the seafloor into microbe-rich sediments, and are consumed by worms, shellfish and other sea scavengers. Those are then eaten by fish, and the microbes continue to circulate throughout the food chain. However, on land, intestinal microbes are excreted as feces, where they often dry out and most die over time.

Not the enterococci, however. These microbes are unusually hardy and can withstand drying out and starvation, which serves them well on land and in hospitals where disinfectants make it difficult for a microbe.

"We now know what genes were gained by enterococci hundreds of millions of years ago, when they became resistant to drying out, and to disinfectants and antibiotics that attack their cell walls," said study leader Michael S. Gilmore, Ph.D., senior scientist at Mass. Eye and Ear and Director of the Harvard Infectious Disease Institute.

(Excerpt) Read more at phys.org ...


TOPICS: Health/Medicine
KEYWORDS:

1 posted on 05/14/2017 8:00:08 AM PDT by BenLurkin
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To: BenLurkin

Fascinating stuff. Great post.


2 posted on 05/14/2017 8:08:44 AM PDT by ComputerGuy
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To: BenLurkin

Makes sense! Thanks for posting.


3 posted on 05/14/2017 8:14:11 AM PDT by JimSEA
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To: BenLurkin

I wouldn’t think it possible to sequence DNA from 400 million year old fossil bacteria.


4 posted on 05/14/2017 8:32:43 AM PDT by Brooklyn Attitude (The first step in ending the War on White People, is to recognize it exists.)
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To: BenLurkin

I am a bit hung up on Antibiotic-resistant microbes existing before antibiotics existed.


5 posted on 05/14/2017 8:36:27 AM PDT by mountainlion (Live well for those that did not make it back.)
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To: mountainlion

“I am a bit hung up on Antibiotic-resistant microbes existing before antibiotics existed.”

Many antibiotics are naturally occuring molecules produced by fungi. Penicillin is one example.


6 posted on 05/14/2017 8:39:04 AM PDT by Brooklyn Attitude (The first step in ending the War on White People, is to recognize it exists.)
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To: mountainlion

“I am a bit hung up on Antibiotic-resistant microbes existing before antibiotics existed.”

Molds with antibiotic properties existed before they were formally identified.

https://en.wikipedia.org/wiki/History_of_penicillin


7 posted on 05/14/2017 8:42:41 AM PDT by FewsOrange
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To: Brooklyn Attitude

Piece of cake, Hillary just offered up some skin cells.


8 posted on 05/14/2017 8:49:39 AM PDT by CodeToad (If it weren't for physics and law enforcement, I'd be unstoppable!)
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To: BenLurkin
As animals crawled onto land about 100 million years later, they took their microbes with them.

Immigrants bringing in diseases.

9 posted on 05/14/2017 8:59:52 AM PDT by MUDDOG
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To: mountainlion

Antibiotics we use to kill certain classes of germs were used by other germs in biological warfare against each other before humans existed.
Like plants producing toxins to discourage insects eating them before we learned about the concept of pesticides.


10 posted on 05/14/2017 9:12:52 AM PDT by tbw2
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To: BenLurkin

perhaps- but we didn’t have the ‘super bugs’ back then very likely because these new superbugs are almost entirely resistant to several antibiotics at once- making them near impossible to control- in the wild, a bug may be resistant to one perhaps two antibiotics over time, but they likely didn’t become super bugs like we have today from overuse of antibiotics


11 posted on 05/14/2017 10:34:21 AM PDT by Bob434
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