I never heard Madonna advocate drugs.
"Molly is a slang term for MDMA, the active chemical in ecstasy, a drug often associated with electronic dance music (EDM) concerts. The crowd erupted in cheers after Madge asked the question (see video of Madonna on stage at the bottom of this article), but not everyone in the EDM community was happy."
Deadmau5 Slams Madonna Over 'Molly,' Ecstasy Reference At Ultra Music Festival
You could be right. I was thinking of the queer sex thing. I’m not going to quote it here.