I saw an episode of Survivorman where he was talking about using smoke to kill foot fungus and mentioned that tobacco smoke was said to be particularly good for it.
A common “cure” for earache that I recall from childhood was blowing cigarette smoke into the problematic ear. Experienced it myself as a child. It actually did feel better, briefly. Why, I have no idea.
I know one thing. When wet, it’s excellent for bee/wasp stings. I keep it in our first aid kit. Handed down in our fam from Cherokee GGMother.