The incidence of birth defects for unrelated couples is 0.00013, in other words 13 out of one hundred thousand. The incidence of birth defects for a pairing of brother and sister is 0.00015 or 15 out of one hundred thousand. serious genetic complications start showing up in the forth generation of inbreeding siblings, the seventh generation of inbreeding first cousins.
Keep in mind that every last one of us are cousins to one degree or another.
Of course your point about inbreeding to the fourth generation tells us what the hell is wrong with a lot of Islam...
I still say it would be one hell of a surprise to find out during a juneteenth celebration you are hooking up with your half sibling....just saying...