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Vitamin B6 May Cut Risk of Parkinson's Disease
Yahoo & Reuters Health ^ | 8/1/06 | Neurology

Posted on 08/02/2006 3:15:31 PM PDT by Dr. Scarpetta

A higher dietary intake of vitamin B6 may decrease the risk of Parkinson's disease, a study suggests.

Among more than 5,000 people, Dutch researchers found those who reported taking in the most vitamin B6 were about half as likely as those who consumed the least to develop Parkinson's disease.

Vitamin B6 is essential for metabolism of protein and proper immune and nervous system function, and is found in both meat and vegetables.

There is evidence that high levels of the amino acid homocysteine could cause damage to brain cells. To see whether higher intake of folate and vitamins B6 and B12, which can reduce homocysteine levels, would also reduce Parkinson's risk, researchers followed 5,289 men and women aged 55 and older who were free of the disease at the study's outset.

During nearly 10 years of follow up, 72 people developed Parkinson's disease, Dr. Monique M. B. Breteler of Erasmus Medical Center in Rotterdam and colleagues report in the journal Neurology.

The researchers found no association between consumption of B12 or folic acid and risk of developing the disease. However, the more B6 people consumed, the lower their risk.

Those in the highest third of vitamin B6 intake were 54 percent less likely to develop the disease compared to those in the lowest third. A closer look suggested that this relationship was only statistically significant for smokers.

The findings suggest that the nutrient could lower Parkinson's disease risk not by affecting homocysteine levels but by protecting brain cells from damage caused by harmful by-products of metabolism known as free radicals, Breteler and her team propose. They note that several studies have shown that smoking actually cuts Parkinson's risk, possibly due to brain-cell-protecting properties of nicotine.

The study doesn't rule out the possibility that B12 and folate could also be protective, the researchers point out. To provide a more definitive answer, they add, studies must be conducted that look at levels of the nutrients in the blood, which is a more sensitive indicator of their effects.

SOURCE: Neurology, July 2006.


TOPICS: Health/Medicine
KEYWORDS: health

1 posted on 08/02/2006 3:15:32 PM PDT by Dr. Scarpetta
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To: neverdem

*Ping


2 posted on 08/02/2006 3:16:58 PM PDT by Dr. Scarpetta
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To: Dr. Scarpetta
They note that several studies have shown that smoking actually cuts Parkinson's risk, possibly due to brain-cell-protecting properties of nicotine.

I never heard that before. Funny, now there's a good reason for people to smoke! Not that I'm going to start smoking any day now....

3 posted on 08/02/2006 3:19:26 PM PDT by Kaylee Frye
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To: wagglebee; texas booster

*Ping


4 posted on 08/02/2006 3:20:33 PM PDT by Dr. Scarpetta
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To: Kaylee Frye

me either...


5 posted on 08/02/2006 3:22:36 PM PDT by Dr. Scarpetta
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To: Kaylee Frye

"Not that I'm going to start smoking any day now...."

I would, if my lungs were up to it.

I didn't want to quit...I had to.


6 posted on 08/02/2006 3:23:41 PM PDT by dsc
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To: Kaylee Frye; Dr. Scarpetta
I never heard that before. Funny, now there's a good reason for people to smoke! Not that I'm going to start smoking any day now...

No need to take up smoking, just use nicotine patches.

7 posted on 08/02/2006 3:34:54 PM PDT by Paleo Conservative
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To: Paleo Conservative

Yeah, I guess that's true!! :)


8 posted on 08/02/2006 3:39:24 PM PDT by Kaylee Frye
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To: Dr. Scarpetta

Red Bull has 250% RDA of Vitamin B6.


9 posted on 08/02/2006 4:20:03 PM PDT by Perdogg
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To: Dr. Scarpetta

Thank you for pinging me to this. The thought that diet could assist in preventing these difficult diseases will give hope to those that have parents that are slowly slipping away.




We have about 160 very active FReepers engaged in a distributed computing project called Folding@Home. It actually grew out from the older Genome@Home project of the '90s.

Folding@Home is dedicated to learning about how the body folds and unfolds proteins to metabolise in a cell. Absolutely fascinating to be able to potentially cure such debilitating diseases as Parkinson's, BSE and Alzheimers.

If anyone is interested in joining our merry band of folders please check out:

http://www.freerepublic.com/focus/news/1676728/posts?page=1

I've pinged our folders to your thread.


10 posted on 08/02/2006 5:31:48 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120))
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To: Perdogg
Red Bull has 250% RDA of Vitamin B6.

Where do you buy that?

11 posted on 08/03/2006 5:26:08 AM PDT by Dr. Scarpetta
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To: texas booster
Thank you for pinging me to this. The thought that diet could assist in preventing these difficult diseases will give hope to those that have parents that are slowly slipping away.

You're welcome. My mother has Parkinson's. I wonder if the B6 could help her at this point.

12 posted on 08/03/2006 5:33:39 AM PDT by Dr. Scarpetta
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To: Dr. Scarpetta
Any grocery/convenient store.
13 posted on 08/03/2006 5:35:18 AM PDT by Perdogg
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To: Paleo Conservative

Interesting thought... Maybe in the future, that would be prescribed!


14 posted on 08/03/2006 5:35:57 AM PDT by Dr. Scarpetta
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To: Perdogg

Thanks for the info.


15 posted on 08/03/2006 5:36:38 AM PDT by Dr. Scarpetta
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