I don't know. There is much history in that town. And while it may seem off to some to bemoan the loss of artifacts and documents, they are not "free" to leave the area when a storm approaches.
I accept that some people could not get out in time (either not getting the message, not being mobile, or not being able to get a vehicle in time); there were also those who chose to stay at home (including Fats Domino and Alex Chilton). I'm sure that some others stayed home (even if they didn't have "hurricane parties" this time). Everyone is worthy of rescue; consider some of them like the hikers who wander off the trail and require vast search expeditions.
Again, historical items were left behind to the rising waters and strong winds. Were they hit by looters? Probably not but the possibility exists. It may be the only way some items could be saved from harm (including sitting in a water soaked room for a week or more).
I also haven't read any mention of the zoo.
If your are talking about the Audubon(sp) Zoo, I am happy to say that the zoo and the animals have fared well at least thus far.