Insofar as the “f-word” originally referred to the act of copulation, using it with any of the leading dummocrap females is rather terrifying to imagine.
However, the word is pretty much meaningless today; it’s just an interjection that gets its interpretation from the context. For the morons in the dummocrap party it’s no more than hate.
Those of us who are smart enough to have more than a ten word vocabulary can do better.
But, don’t use that word around my wife unless you want to go to bed without dinner...and dessert.