This really should not have even been a question in the nurse's mind. Especially since Nina Pham got it after being geared up. After the obvious incompetence at the CDC, she's going the play "Mother May I" with those clowns? Would you take life and death advice from an Obama appointee? Yeah, neither would I.
I think w/the mixed messages and lack of guidance from the CDC and/or anyone else in authority it was predictable that things would go very wrong. I don’t know how experienced this nurse is; however, she appears to be very young like the other infected nurse. I would definitely cut them some slack; as the real culprit here is the CDC and probably the senior hospital staff for not issuing clear and proper guidance; or demanding same in the case of the senior hospital staff.
These nurses are now dealing w/the fact they were deliberately exposed (without proper guidance or equipment) to a disease that is lethal in 50% to 90% of cases and for which there is no known cure. They likely feel like they have been betrayed by both the CDC and their senior management People tend not to think clearly or rationally in these situations and these nurses haven’t had the benefit of any competent leadership IMHO.
To answer your question, no, I do not and would not trust the senior appointed officials at CDC. There are likely a lot of competent staff there; but, that would be amongst the career staff. Unfortunately, Dr Frieden is an appointee and obviously a politician first and foremost; and his arrogance only adds to the problem. He is the worst possible person for the demands of the current health crisis.