My wife’s cancer started in lungs, with no symptoms at all, she never smoked, but growing up in her family of 8 people, 6 were smokers. Before any symptoms appeared the cancer had already spread to ribs, brain, lymph nodes. She survived 5 years and 10 months post diagnosis of stage-4 which is as good as it can be.
Sorry about your wife e12. You clearly miss her badly.