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Yikes! Covid in the house!
My Fingers and Brain | 24 December 2021 | Me

Posted on 12/24/2021 5:08:19 AM PST by Magnatron

All I want for Christmas is…

Covid?

Our twenty-something son came home for the holidays with the sniffles and we had him take a home Covid test, which came up positive. He’s going to the health department today for a formal test, but it does appear that we have an uninvited guest in the house.

My wife, 16-year-old son, and myself are not vaccinated. We are going to keep our distance and take some basic precautions. We will also be consulting our MD for advice and get ourselves tested after a suitable incubation period. We are taking zinc, vitamin D, and aspirin.

We can’t ask our son to leave. He just went through a bad breakup with a long term girlfriend. Things are also a bit complicated due to his dog being here with him and she’s mixing it up with our dogs.

Again, we’ll be seeking some real medical advice, but I’m curious:

What would any of you do in this situation?


TOPICS: Chit/Chat; Health/Medicine
KEYWORDS: seeadoctor
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To: joethedrummer

P.s. - do NOT panic and run to the hospital!

THAT is what’ll get someone killed.


121 posted on 12/24/2021 9:26:30 AM PST by joethedrummer (We can’t vote our way out of this, folks..)
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To: KosmicKitty

Sorry to hear…try to have a Merry Christmas!


122 posted on 12/24/2021 9:27:23 AM PST by angelrod
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To: genetic homophobe

Bookmark


123 posted on 12/24/2021 9:48:00 AM PST by aquila48 (Do not let them make you "care" ! Guilting you is how they control you. )
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To: Magnatron

ALTERNATIVE SAFE WAYS TO KEEP YOUR RESISTANCE UP & FIGHT COVID -19. AS WELL AS “VARIATIONS” AND A HOST OF OTHER INFECTIONS INCLUDING THE FLU.

THIS REGIME WILL “NOT” PREVENT YOU FROM CATCHING THIS CRAZY VIRUS BUT IF YOU DO, IT WILL HELP TO SHAKE IT OFF FAIRLY QUICK, FOR SOME PEOPLE IT WORKS SO WELL THEY DON’T EVEN FEEL THEY GOT IT. BESIDES IT WILL ALSO WORK AGAINST OTHER RELATED VIRUSES; NOT ONLY THAT, BUT WILL BENEFITS YOUR HEALTH AS WELL, IF YOU CATCH THIS VIRUS OR NOT. EITHER WAY YOU WIN. ALONG WITH IT YOU WILL HAVE ACQUIRED NATURAL IMMUNITY WITHOUT ANY SHORT OR LONG TERM ADVERSE SIDE EFFECTS.

There are other ways and means to enhance your resistance against viruses including that by now infamous covid-19 virus aside from taking any of these “Quick” developed vaccines utilizing a messenger RNA. So far science has not evolved far enough yet to be certain how the human body will react many month or years down the road once we start tinkering around with our immune system and how our bodies will react should we encounter mutated strains of similar viruses.

Below is a list of vitamins as well as nutrients SUGGESTED BY A PHYSICIAN to enhance your resistance, they are harmless and even beneficial to your body unless someone goes crazy and over doing it. Even so they will NOT protect you from getting any specific viruses; neither will any of those new “QUICK” developed vaccines. But not only will they make you more resistant but also help you to overcome the effects of such a virus more quickly, should you have bad luck getting it. And once you are over it, your natural immune system will take over and protect you considerably better than any vaccination, this according to a statement by Merck. The CATCH is to have these vitamins/nutrients in your system BEFORE you think you have caught this virus, as time is of essence so your system starts fighting the virus BEFORE it gets a chance to do any damage.

A suggestion to the wise, take some time and read up on each of these suggested components which is freely available on the internet.

Vitamin D — Vitamin D supplements are readily available and one of the least expensive supplements on the market. All things considered, vitamin D optimization is likely the easiest and most beneficial strategy that anyone can do to minimize their risk of COVID-19 and other infections, and can strengthen your immune system in a matter of a few weeks.

N-acetyl cysteine (NAC) — NAC is a precursor to reduced glutathione, which appears to play a crucial role in COVID-19. According to one literature analysis,7 glutathione deficiency may actually be associated with COVID-19 severity, leading the author to conclude that NAC may be useful both for its prevention and treatment. For best results should always be taken with two to three times the amount of vitamin C. DO NOT GET IT MIXED UP WITH ACETYL L-CARNITINE

Zinc — Zinc plays a very important role in your immune system’s ability to ward off viral infections.

Like vitamin D, zinc helps regulate your immune function8 — and a combination of zinc with a zinc ionophore, like hydroxychloroquine or quercetin, was in 2010 shown to inhibit SARS coronavirus in vitro. In cell culture, it also blocked viral replication within minutes.9 Importantly, zinc deficiency has been shown to impair immune function.

Melatonin — Boosts immune function in a variety of ways and helps quell inflammation. Melatonin may also prevent SARS-CoV-2 infection by recharging glutathione11 and enhancing vitamin D synthesis, among other things.

Vitamin C — A number of studies have shown vitamin C can be very helpful in the treatment of viral illnesses, sepsis and ARDS,12 all of which are applicable to COVID-19. Its basic properties include anti-inflammatory, immunomodulatory, antioxidant, antithrombotic and antiviral activities. At high doses, it actually acts as an antiviral drug, actively inactivating viruses. Vitamin C also works synergistically with quercetin.

Quercetin — Quercetin is the most abundant dietary flavonoid, found enriched in cranberry, onions, blueberry, apples, and tea. As a polyphenol compound, it is ALSO considered a potent iron chelator. A powerful immune booster and broad-spectrum antiviral, quercetin was initially found to provide broad-spectrum protection against SARS coronavirus in the aftermath of the 2003 SARS epidemic,14,15,16 and evidence suggests it may be useful for the prevention and treatment of SARS-CoV-2 as well. Not only that but quercetin also acts as an ionophore for zinc similar to hydroxychloroquine, in a matter of speaking it will unlock the cells to let the zinc in where it can attack the virus . It is also a good pain killer and better for the human body than Aspirin, what helps to subdue arthritis pain. I is good for sinus infection, in other words if you happen to have a runny nose. Past studies have also shown that quercetin showed potent ability against some viruses, such as enterovirus, Middle East respiratory syndrome coronavirus (MERS-CoV), and the severe acute respiratory syndrome coronavirus (SARS-CoV).

B vitamins — B vitamins can also influence several COVID-19-specific disease processes, including17 viral replication and invasion, cytokine storm induction, adaptive immunity and hypercoagulability.

LYSINE
When lysine blocks enzymes it inhibits the spread of the virus in the body by limiting the effect of weakening this connective tissue. An adult may take 2-3000 mg per day of lysine while trying to beat a virus.

SUGGESTED DOSAGE

All components as suggested are individually obtained and freely available and if used with some common sense are not harmful and if anything beneficial to your health. However it is a good idea and highly recommended to read up on each component, as there is plenty of information available on the internet. You may be surprised to find out and learn about the many benefits they provide to your health.
Here is a suggested approximate dosage for each.

Vitamin D 1500 IU

Malatonine 3mg to 6mg suggested about one hour before you go to sleep.

QUERCETIN 500 mg to 1000 mg

NAC 500 mg to 1000 mg (N-Acetyl-Cysteine)

Zinc 50 mg

Vitamin C 1500 mg or MORE !! but always should be to two three times as much as NAC

LYSINE

1500 mg to 3000mg

Vitamin B complex

So far whoever has been taking this regime of supplements and may have had a brush with this virus, shook it off fairly easily and quickly and the most important thing was that in the process such a person also acquired natural immunity. Not only that but at the same time this regime also helps to ease the effects of the regular flu.

Some of user’s comments:

Latest J&J Vaccine Info: Alex Berenson
4/15/2021, 10:49:29 AM • 27 of 28
Chauncey Gardiner to saintgermaine
Good post.
I have been on that same vitamin regimen since April 2020 along with approx 25 friends/family members. All of us socially active...restaurants, church, weddings, travel, etc. In other words, we’ve not changed our lives the past year. Not a one of us has tested positive and not a one has even had a cold. I’ve added hydroxychloroquine 200mg each Sunday starting about 6 mos ago.

Mississippi man partially paralyzed, unable to talk after J&J vaccine
4/16/2021, 6:48:45 PM • 37 of 39
upchuck to saintgermaine

Excellent regimen. Pretty much what I’ve been doing. I have been taking 5000 iu of Vit D3 per day for years and have never been sick (thank you Lord). With the China Virus, I upped it to 10,000 iu. I think zinc and quercetin are the most important.
10,570 DEAD 405,259 Injuries: European Database of Adverse Drug Reactions for COVID-19 “Vaccines”

5/21/2021, 7:41:23 AM • 52 of 52
jimjohn to saintgermaine
Been on similar regimens since August of 2020. Attended parties public events even a professional football game. Oh, and I fall in the high-risk category. Also posted recently about hearing friends and associates who’ve taken the jab complain about the after effects. Also note that my position would not recommend that I take this experimental vaccine.

Trump Girl Kit Cat to saintgermaine
My Doc put myself and EVERY patient he had on Quercetin, C, D3, Zinc, and NAC from day one he has not had ONE SINGLE patient catch this virus, I also put my 92 year old mom on it I NEVER miss a day!! My mom had a small stroke about 4 months ago neither of us vaccinated I had to take her to emergency and was worried because hospitals are an absolute petrie dish of germs we both spent 4 days in the hospital no masks in room AND we both came home just fine this supplement regimen works!!!


124 posted on 12/24/2021 10:01:06 AM PST by saintgermaine (Saintgermain the time traveler)
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To: Vermont Lt

Have you never heard that 2 heads are better than one?

People ask other people their opinion on a subject to get different ideas, are you truly too dense to understand that?

Just because a person gets advice doesn’t mean they must follow up and act on that advice. I have learned so much from real peoples experiences on this thread.

What baffles me is why are you a Freeper.


125 posted on 12/24/2021 10:01:07 AM PST by Ferndina
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To: DannyTN

Yep. I believe they thought it might function as a protease inhibitor against viral replication. Not really.

It just proves the more we know the less we know. That is real science!


126 posted on 12/24/2021 10:04:37 AM PST by volunbeer (Find the truth and accept it - anything else is delusional)
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To: saintgermaine

I was taking NAC but stopped. Based on what I am reading, NAC is fantastic if you have Covid but not all that beneficial if you do not.

I strongly believe that the two most important supplements (or three) are vit D, quercetin, and zinc. I take the quercetin that contains zinc twice daily and so far so good despite my daughter and I being the only two that did not catch it in our family, work, and social circle.

I do have a good stock of NAC and have given it to friends who contracted it. NAC definitely works after infection but not sure it is of much benefit as a prophylactic. It clearly has a benefit to the symptoms of Covid though! Your mileage may vary.

It is criminal that corporate medicine and big pharma have refused to recognize the benefits of simple supplements in the fight against Covid. The vitamin D thing is really inexcusable to me because the science is so clear of the benefit AND the fact that most negative outcomes were deficient.


127 posted on 12/24/2021 10:11:12 AM PST by volunbeer (Find the truth and accept it - anything else is delusional)
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To: volunbeer

Yeah, they asked a lot of good questions and did their best to answer them.

I think without understanding how it works, I would want to go with some of the other approaches. I just don’t like the idea of reducing stomach acid. I want that acid to destroy any virus particle that gets that far.

Plus I’m wondering what effect that has on the absorption of any other supplements or drugs you are taking.

Just my opinion.


128 posted on 12/24/2021 10:54:48 AM PST by DannyTN
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To: metmom

😬


129 posted on 12/24/2021 11:01:50 AM PST by Mr.Unique (My boss wants me to sign up for a 401K. No way I'm running that far! )
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To: metmom

metmom wrote: “Why ruin perfectly good natural immunity?”

Evidently, they haven’t been infected so there is no natural immunity. Most of the evidence supports vaccination as increasing the protection from natural immunity.

metmom wrote: “You’re an idiot if you advise vaccinating in the middle of an epidemic and everyone knows that. If they have been exposed, it’s too late for the vax.”

Vaccination is usually how epidemics end and epidemiologists know that. Exposure doesn’t mean they have caught covid. They should leave the choice of vaccination to their doctor, not a bunch of internet wannabees.


130 posted on 12/24/2021 11:10:14 AM PST by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: angelrod

Thank you,

Have a wonderful Christmas too


131 posted on 12/24/2021 11:43:55 AM PST by KosmicKitty (i am not responsible for gremlins attacking this tagline)
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To: Magnatron
the tests are not totally reliable....in addition to your vitamins, don't forget to load up on Vit C....2000mg daily to start....Vit D probably around 5000 units a day....

if your Vit D level is at 50 or so, the virus is limited...

God bless and good luck....youse guys will be fine.

132 posted on 12/24/2021 11:46:48 AM PST by cherry
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To: metmom

Thank you for the spelling advice.

I probably had some assistance from my phone but it’s nice to know you have my back.


133 posted on 12/24/2021 12:04:47 PM PST by dangerdoc
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To: cherry

I started taking 5000 iu vit D and 1000 mg of vitamin C daily, I didn’t get COVID but I got my first kidney stone. I expect it was a calcium oxalate stone. Vitamin D increases calcium and Vitamin C increases oxalate.

I lowered the vitamin C to 500, increased fluids and started vitamin K2. So far no more stones.


134 posted on 12/24/2021 12:10:40 PM PST by dangerdoc
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To: Magnatron

He will have to take Vit C D3 and zinc for the rest of his life. Boost that D3 level. Sorry to hear that, but you and your wife need to be protected now.


135 posted on 12/24/2021 12:36:20 PM PST by The MAGA-Deplorian (Democrats are lawless because Republicans are ball-less!)
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To: volunbeer

First of all, thank you for your reply as it is always interesting to hear what other people think. Overall I agree with your suggestions however I positively would include vitamin C. As far as NAC is concerned, not directly but in a roundabout way I would consider it a form of prophylactic as it is powerful booster of your resistance to a variety illness as the human body will convert it to glutathione which does the actual job. I added NAC to my daily intake about ten, twelve years ago when the H-1 N-1 virus made its round and some one suggested that NAC will do just about as good or better than a shot. Prior to that I used to get a cold every so often along with getting choked up a runny nose etc. but since including NAC, knock on wood I have been spared. I have included some info about NAC you may find useful. Stay healthy and well.

N-acetyl Cysteine a wonder drug

For more than three decades, a safe, low-cost compound has provided millions of people relief from the coughing, wheezing, and thick phlegm associated with cold and flu. Of course, pharmaceutical companies long ago co-opted it for profit by incorporating it into various patented drugs.

The sad consequence is that most aging individuals have never heard of it. Even many doctors remain unaware of its potential role as a frontline defense against some of today’s most deadly public health threats, including:

• Acetaminophen toxicity and acute liver failure: the number one cause of acute liver failure in the United States.1

• Influenza: whose victims are primarily aging individuals—three quarters of all flu-related deaths occur in the elderly.2

• Chronic obstructive pulmonary disease: the fourth-leading cause of death in the United States (includes emphysema and chronic bronchitis).2

• Helicobacter pylori: the bacterial culprit behind stomach ulcers, and a potentially lethal pathogen closely linked to malignant gastric cancer, the second most frequent cause of cancer death worldwide.3

Fortunately, renewed clinical interest in its broad-spectrum benefits is yielding fresh data on promising interventions for this safe, effective compound.

In this article, you will discover the latest research on N-acetyl cysteine (NAC), a readily available, inexpensive amino-acid derivative with four decades of scientific validation. You will learn of its role in restoring intracellular levels of one of the body’s most powerful antioxidant defenses, glutathione (GSH). You will also find out how 600-1,800 mg of NAC daily may act as an effective intervention against a constellation of chronic, degenerative diseases, including impaired glucose control and cancer.
An Underutilized Intervention

NAC is a slightly modified version of the sulfur-containing amino acid cysteine. When taken internally, NAC replenishes intracellular levels of the natural antioxidant glutathione (GSH), helping to restore cells’ ability to fight damage from reactive oxygen species (ROS).

NAC has been used in conventional medicine for more than 30 years, primarily as a mucolytic (mucous-thinner) inhaled to manage conditions such as cystic fibrosis, in which mucous is abnormally thick and tenacious. While there is little in the scientific literature to support its use as an inhalant, NAC administered in this form remains highly popular among experienced pulmonary speclialists.4,5

NAC given intravenously or orally, on the other hand, saves lives every year as a treatment for acute poisoning with acetaminophen-containing pain-relieving drugs. Acetaminophen is sold as Tylenol® and combined with other drugs to create analgesic compounds, including Vicodin® and Percocet®.6 Overdoses with acetaminophen are the number one cause of acute liver failure in the United States.6-8 Too much acetaminophen overwhelms the body’s glutathione reserves, which creates widespread and irreversible liver damage. NAC quickly restores protective levels of glutathione, averting catastrophe.7

Beyond this particular application, NAC has remained a relatively obscure and poorly understood compound until quite recently. Scientists all over the world are now beginning to understand just how vital glutathione metabolism really is, and how many disease states involve glutathione deficiency.9 According to Stanford University’s Dr. Kondala R. Atkuri, “NAC has been used successfully to treat glutathione deficiency in a wide range of infections, genetic defects and metabolic disorders, including HIV infection and COPD. Over two-thirds of 46 placebo-controlled clinical trials with orally administered NAC have indicated beneficial effects of NAC measured either as trial endpoints or as general measures of improvement in quality of life and well-being of the patients.”9

Multitargeted Regulation of Gene Expression

Much of NAC’s beneficial activity derives from its capacity to modulate expression of genes for myriad signaling molecules in the inflammatory response.10-12 NAC inhibits expression of pro-inflammatory cytokines following exposure to bacterial cell components and infection with influenza A virus.13,14 NAC suppresses the “master signaling molecule” nuclear factor-kappaB (NF-kB), which in turn prevents activation of multiple inflammatory mediators.15,16 NAC also regulates the gene for COX-2, the enzyme that produces pain- and inflammation-inducing prostaglandins in a wide array of chronic conditions.17

NAC’s ability to replenish the intracellular glutathione supply and mitigate oxidative damage is a separate and equally powerful mechanism that affords protection against DNA damage and cancer development, even in smokers.18 NAC’s inhibition of inflammatory cytokine production is another mechanism credited with cancer reduction in various body tissues.19

Gene expression modifications induced by NAC may also help reduce the acute oxidant-provoked inflammatory response following exercise, making vigorous activity safer and even more beneficial.20 Finally, obesity-associated insulin resistance, which arises from production of inflammatory signaling molecules in fat cells, can be sharply mitigated by NAC through regulation of their genes.21,22

The recent explosion of scientific evidence for NAC’s multi-targeted health benefits is matched only by the willful ignorance of the mainstream medical community. Some even question its safety, despite nearly 40 years of use in a variety of clinical conditions, which have established the safety of this compound, even at very high doses and for long-term treatments.18 One study demonstrated the safety of 1,800 mg per day for 142 days, while another study demonstrated the safety of 2,800 mg per day for 3 months.23
Here is a selection of the most compelling information about NAC from the global scientific community—information that should convince even skeptical mainstream physicians.

WHAT YOU NEED TO KNOW: N-ACETYL CYSTEINE’S BROAD-SPECTRUM BENEFITS

• Long relegated to infrequent use in unusual circumstances, the amino acid-derived compound N-acetyl cysteine (NAC) has drawn increased scientific attention.

• NAC replenishes levels of the intracellular antioxidant glutathione (GSH), which is often deficient with advancing age and in chronic illness.

• NAC also regulates expression of scores of genes in the pathways that link oxidative stress to inflammation.

• These dual effects give NAC a unique role in the prevention and treatment of many common diseases, both acute and chronic.

• NAC can protect against avian influenza and more common seasonal flu symptoms.

• NAC reduces the frequency and duration of attacks of chronic obstructive pulmonary disease (COPD) and may slow the clinical course of idiopathic pulmonary fibrosis (IPF).

• NAC protects tissues from the effects of exercise-induced oxidative stress, adding value and safety to your workout.

• NAC improves insulin sensitivity in people with some of the most difficult-to-treat metabolic disorders.

• NAC blocks cancer development at virtually every step in the process, and through multiple mechanisms, making it an important cancer chemopreventive agent.

• NAC fights the stomach infection Helicobacter pylori on two fronts, inhibiting the organism’s growth while reducing production of inflammatory cytokines that can lead to gastritis and cancer.

• Though most individuals gain benefits from 600-1,800 mg/day, clinical studies have found that doses of up to 2,000 mg/day are safe and effective. A recent study demonstrated the safety of 2,800 mg/day for 3 months in patients with COPD.23
Potent Influenza Protection
H5N1 influenza, or bird flu, is a lethal and potentially pandemic infection that produces the massive release of inflammatory mediators aptly called the “cytokine storm.”24 Other more common forms of influenza also act by triggering massive cytokine releases that inflame vulnerable lung tissue. In early 2010, it was discovered that NAC offers dual protection against bird flu. It inhibits both virus replication and expression of pro-inflammatory molecules in cells infected with H5N1 virus, holding out the promise of effective protection in the event of a global avian flu pandemic.13

By now I have been taking NAC for about eight years along with many other nutrients/ vitamins and it has worked like a charm. I used to get head colds along with runny noses, all choked up and slept in a recliner as I couldn’t breath. Since I been taking it I haven’t had any of these problems along with it no flu. Should you decide taking it is recommended to take about at least twice the amount of buffered ascorbic acid in order to remove any by products which are created as NAC is doing its job. On a daily basis I been taking about 2 + grams of NAC along with about 6 grams +or – of buffered C.. Or about ¾ tsp of NAC and 1 heaping tsp of buffered C. I have a hunch taking this stuff may save you a lot of time and effort as well as expenses driving back and forth to a doctor, not to mention you also will feel better. Should you decide on taking it I can give you the sources from where you can get it in bulk and powder form very reasonable.

NAC has also proven effective against seasonal influenza and flu-like illnesses. In a large study of older adults who took 600 mg twice daily for 6 months, only 25% of those experienced influenza-like episodes, compared with 79% in the placebo group.25 Even those with flu symptoms experienced a significant reduction in illness severity and length of time confined to bed. All subjects tolerated the treatment well. The study’s lead author, Dr. Silvio de Flora, commented that “Administration of N-acetyl cysteine during the winter, thus, appears to provide a significant attenuation of influenza and influenza-like episodes, especially in elderly high-risk individuals.”25

Influenza is a complex disease with multiple targets, most notably inflicting damage to lung tissue through extreme oxidative stress and inducing genes for a large variety of inflammatory mediators.26,27 At the microscopic level the destruction is vivid. The influenza virus causes such intracellular turmoil that the term “cell boiling” has been used to describe the devastation.28 But pretreatment of cells with NAC significantly offsets these effects, reducing the oxidative and inflammatory burden within lung tissue through multiple mechanisms.26,28-30

NAC has now been shown to protect laboratory mice from lethal influenza infection, synergistically enhancing the effects of several common antiviral medications.31,32 And a nutrient mixture containing NAC, green tea extract, certain amino acids and micronutrients had powerful antiviral effects in cultured cells, rivaling those of prescription flu drugs such as amantadine and oseltamivir (Tamiflu®).33,34 The NAC-based mixture actually affected viral replication for a longer period than did the drugs.34
In the words of prolific medical theorist Mark F. McCarty, “The most foolproof way to promote survival in epidemics of potentially lethal influenza is to target… intracellular signaling pathways which promote viral propagation or lung inflammation.”30 McCarty goes on to cite NAC’s benefits as a multitargeted supplement with precisely those attributes. NAC at doses of 600 mg twice daily may significantly reduce the risk of a devastating bout of influenza.

NAC AND PULMONARY ARTERIAL HYPERTENSION: A REAL RISK?
N-acetyl cysteine (NAC) produces numerous beneficial effects in many human tissues both by supporting natural antioxidant systems and by favorably affecting expression of genes involved in the inflammatory response.

A 2007 study in laboratory mice, however, has raised a theoretical concern that chronic NAC administration in those animals might produce a condition called pulmonary arterial hypertension.76 Here is a review of that study and some reassuring facts:

The Issue
Pulmonary arterial hypertension (PAH) is an elevation in blood pressure in the arteries leading from the heart to the lungs. It is one of the consequences of chronic hypoxia (lack of sufficient oxygen) that occurs in a number of chronic cardiovascular and pulmonary (lung) diseases. It also arises in people with obstructive sleep apnea.77-79 It is a rare condition, but when it occurs it can be difficult to detect and may be fatal if untreated.79 Its causes remain unclear, but they seem to involve signaling molecules produced during hypoxia; some of those molecules include those involved in detecting and responding to oxidative stress.80

The Concern

Scientists at the University of Virginia School of Medicine were studying the molecular signaling involved in hypoxia-related development of PAH when they observed what seemed to be a concerning finding: mice treated with NAC over periods of 3 weeks were developing PAH that mimicked the effects of chronic hypoxia.76 The scientists were not studying the effects of NAC itself; they were simply using it to measure other nitrogen-related transfer reactions in blood. And the doses they used correspond to a human dose of about 20 grams (20,000 mg) per day—far above any known supplement recommendation. Nevertheless, parts of their report were cited in one commentary as raising “the concern that chronic NAC therapy may induce similar vascular pathology in patients.”81

Is this a realistic concern, or is it a laboratory anomaly? Here’s the evidence to date.
The Evidence

The Virginia team’s mouse study was published in 2007. Now, nearly 3 years later, there has not been a single additional publication connecting NAC therapy with PAH in either animals or humans. In reality, a substantial amount of science both before and after the 2007 report suggests just the opposite—that NAC may be instrumental in reducing, not increasing, the oxidant-induced blood vessel changes that occur in PAH. Here are the highlights:
• In one of the original animal studies demonstrating that oxidative stress contributes to development of PAH induced by hypoxia, NAC actually reduced the heart and lung changes that lead to PAH, in part by reducing toxic peroxide molecules.80

• NAC, given before and at the beginning of experimental hypoxia, was effective at preventing PAH, including deadly heart muscle changes, in laboratory rats.82

• NAC protects experimental animals’ lungs from the acute lung injury caused by a variety of mechanisms involving hypoxia, oxidant stress, and inflammation, through its joint antioxidant and anti-inflammatory actions.83,84

• A study of human volunteers revealed that NAC supplements at 1,800 mg/day increased the healthy respiratory response to hypoxia,85 which normally declines strongly with age and may contribute to PAH.86 Although this study was cited by the Virginia group as supporting their concern about NAC inducing PAH, no such evidence is presented in the human study, and in fact the authors conclude that NAC treatment “may be useful for elderly subjects and for patients who have other conditions with an oxidative shift… such as coronary heart disease and malignant diseases.”85

The Recommendation

There have been no further publications supporting this one-time observation made in an animal model using doses 10-20 times those suggested for long-term human supplementation. No human study has uncovered any evidence for a similar effect in humans. By contrast, there have been numerous studies demonstrating human benefit from NAC supplementation at moderate doses (1,200-1,800 mg per day) over the course of nearly 4 decades. At this point the known benefits of NAC appear to outweigh any potential risks. As with all supplementation, people should communicate clearly with their healthcare providers about how supplements and medications might work jointly to influence their health.


136 posted on 12/24/2021 1:15:31 PM PST by saintgermaine (Saintgermain the time traveler)
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To: Ikeon
“I lost 10 pounds when I had it”.. ummm, can you send me some spit? Its for a friend..

I had it back in Sept.

Alas, my spit is just spit, again.

I test twice a week for work. As of 2 days ago, I am negative Covid.

137 posted on 12/24/2021 1:30:14 PM PST by occamrzr06
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To: Pollard

It takes a while for vit. D3 to get into your system but there is a prescription version that acts more quickly. Also, there is a vitamin c that is iv infused that bypasses the digestive system and so gets to the cells more efficiently. Don’t wait to begin the vitamins if using the over the counter versions since it can take weeks for them to correct any existing deficiencies. Bringing those nutrients up now helps you to weather illness better.

See the frontline link above and learn.


138 posted on 12/24/2021 2:08:01 PM PST by PrairieLady2
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To: Georgia Girl 2; Magnatron
See if your doctor will prescribe a prophylactic dose of HCQ for other household members or make some in your kitchen like we did and take it daily.

The main part of HCQ you're looking for is quinine. So...:

https://pinchandswirl.com/homemade-tonic-water-for-the-ultimate-gin-and-tonic/
139 posted on 12/24/2021 2:11:10 PM PST by Svartalfiar
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To: Svartalfiar

We take the HCQ in tonic water which has quinine.


140 posted on 12/24/2021 5:39:59 PM PST by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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