Reminds me of the movie WHISKEY GALORE! 1949. Just with a truck and not a ship.
I'll see you your "Whiskey Galore" and raise you with the "Hallelujah Trail" (1964 John Sturges 'Epic' Western). Not an all-time great, but when you have Sturges directing Burt Lancaster & Lee Remick in a comedy about a whiskey supply wagon train to Denver protected by the US Cavalry and threatened by American Aborigines (aka Native Americans, American Indians etc.) and Temperance women, the movie does leave fond memories.