McGregor can definitely push Mayweather against the ropes or into a corner and land a few body shots before the ref steps in and breaks them up. Mayweather will almost certainly try to pot-shot with one or two shots from the outside and try to out-quick McGregor then escape to a safe distance.
It’ll be interesting to see who has the better game plan. Both are remarkable athletes.
The odds certainly greatly favor Mayweather. However, if anyone is going to beat him, it is likely to be someone who has a highly unconventional style. Floyd is so skilled at living in the pocket, giving his opponent the shoulder, then popping out a few quick punches before he slips away. He can, and does, do that for 12 rounds completely neutralizing the other fighter’s aggression. What Floyd is not as adept at is dodging punches from ridiculous angles, punches that no trained boxer would throw. That’s where McGregor has a chance. If Mayweather’s defense doesn’t work as usual, we’ll see him really put to the test.