I worked in a big city ER for years.Something we used to see all too often was what we called "toxic sock syndrome".When suffering from this syndrome (street people,mentally ill,elderly) you've been wearing your socks (or,in one case I saw,your bra) for so long that when you take them (it) off part of your skin goes too.The skin has become "interwoven" with the fabric of the garment.
And then there's the smell.