Uh-oh ... Rick’s gonna finally lose his hand!
I’m going with Glenn gets killed, per the comics (second bet would be Daryl, because they haven’t done much with his character lately)
and Rick keeps his hand.
Rick losing his hand in the comics was shocking and a big deal when it happened, but then became a nothing as the series continued. It would be the same on TV, but then they’re stuck doing special effects on every episode to make him handless - and for no particular benefit. Sure they did it for Hershel, but he wasn’t in nearly as many scenes as Rick. .