That’s not L.H.O.O.Q. That piece is a print of the Mona Lisa with a penciled goatee and inscribed with the title. When pronounced correctly the title in French basically means “she has a hot ass”.
Correct,Link from poster is this:
Etant donnes (1946-66)
Artwork description & Analysis: Installed behind a heavy wooden door that was found in Spain and shipped to New York, Etant donnes consists of a diorama viewed through two eyeholes. The scene depicts a nude woman, possibly dead, with her legs splayed, holding an illuminated gas lamp. A mountainous landscape, based on a photo Duchamp shot in Switzerland, creates the background setting. Built in secret over a period of more than twenty years, Etant donnes is considered Duchamp’s second major work. He made an entire manual for its installation, which is reproduced in facsimile and available in print. At first glance, Etant donnes is a direct reference to Courbet’s painting, Origine du Monde (1866). Yet upon closer consideration, the piece can be viewed as a reflection on the boundaries between artist and spectator, as a means to question self-consciousness, or as a meditation on spiritual purpose through the symbolism of a lit lamp.
Painted wood, latex, and fabric - Philadelphia Museum of Art