There is not a drug that cures opiate or alcohol addiction. I treat many such patients, and believe me if there was an easy answer, I would use it. Naltrexone can help, but it is not a magic button. Suboxone can also help, but it is very similar to methadone - it replaces opiates and is tapered gradually.
Are these used mainly for detox purposes?
Do you have experience with Naltrexone vs Nalmefene?
I would say most of the patient reviews say Naltrexone is life-changing or did nothing. I think every alcoholic should give it a try. The side effects are miniscule compared to the benefit if it works for that person.