[CaptainK]

Acetaminophen can be a danger to the kidneys and liver. Not sure about ibuprofen causing the same kind of damage.

[entropy12]

Acetaminophen certainly has bad record for kidney & liver damage. But every factory made pill has some bad effect on our bodies, only the proportion varies. Swallow pills only if there is no other alternative possible. I am betting on good nutrition and regular exercise.

[corkoman]

NSAIDs can reduce kidney function but that is a transient effect and normal function returns after you stop taking it. At very high doses you can get kidney damage but at those doses your hearing loss would be a more apparent problem.

Acetaminophen does not have this effect on kidney function but at >3.5 grams/ day causes slight but measurable liver damage. At very high doses your liver cannot be saved and you are goner.

[Nervous Tick]

>> Acetaminophen can be a danger to the kidneys and liver. Not sure about ibuprofen causing the same kind of damage.

My understanding is, acetaminophen (e.g. Tylenol) is metabolized in the liver, whereas ibuprofen is removed by the kidneys.

That’s why I prefer ibuprofen... I prefer to use my liver for metabolizing other things. :-)

[Boogieman]

Pretty much every drug can cause liver and kidney damage, I think.