The big mistake the Nazis made in Russia was not to divise a ‘Divide and Conquer’ strategy. Many even welcomed the Nazis originally as liberators, but the Nazi brutality towards them, made it virtually impossible to foster and meaningful Russian resistance to Stalin.
The civil policies they adopted were unwise, but they were a product of the world view of national socialism. The results were bound to cause opposition. The activities of the Einsatzgruppen made sure that opposition to Nazi rule would be very bitter.