Posted on 08/31/2014 1:18:08 PM PDT by nickcarraway
As with anything in bio genetics, it changes every year or so.
Good luck. I appreciate your dilemma. A cure is coming.
The other research, using skin cells, looks promising. This one, not so much.
Prevention for type one diabetes has been known for a long time. Dosing infants with 2000 IU’s per day of vitamin d3 during the first year prevented 80% of the type one cases that should have appeared during the succeeding 20+ years.
Rodents knock outs that are engineered to become type ones are prevented from becoming type ones by dosing with d3
while they are pups.
Type one cases that should have appeared? What does that mean? How do you know if a child should become a type one?
The incidence rate of type one diabetics in Finland is substantially higher than the rate of incidence in Asian populations. The incidence of type one diabetes in Asian and Scandinavian populations is well known to the epidemiologists that study these fact patterns. The d3 study was done in Finland and the rate of incidence of type one diabetes among the d3 group was only 20% of the incidence of type one among the control group (untreated with d3).
Exposure to UVB would do the trick... too bad popular “wisdom” has par3nts smearing UV blockers on their kids. Hand sanitizer is another downfall.
Wish I would have known. I have two type 1 children with no history of type 1 anywhere in the family. I sunscreened them but not to the point where they didn’t tan. Big believer in sunshine.
Having said that, they've been talking about encapsulation for twenty years, so it would take more than this to get me excited anyway.
I hope their plan is to use one’s own stem cells for the treatment.
I understand and respect your decision. My hope is that if this trial is successful then a way can be found using adult stem cells. I did not realize they had been talking about encapsulation for so long; but I do believe they will beat diabetes, or at least find a much better way to treat it.
The one that had my interest was encapsulated swine islets. The problem was that they didn’t have enough of the pigs that they needed.
There are a couple of companies that have managed to tease adult stem cells into islets. I don’t know why they wouldn’t just use those. Combine that with encapsulation and you’ve got a treatment, free of morality issues.
For years, my son was the only one in two families with T1D. This year, we’ve got two more on hubby’s side.
Seems you are correct sir.
http://viacyte.com/technology/stem-cell-engineering/
ViaCyte was the first company to engineer human embryonic stems cells into definitive endoderm, the gatekeeper cells that differentiate into pancreas, liver and other cells, tissues and organs.
It appears that these ARE ESC. That’s a shame. I am willing to bet once the cells are developed they will be able to use adult cells. As I indicated in my opening comment—the bio engineering world is changing so fast it is tough to keep up.
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