One that particularly has annoyed me recently is this: There is a federal law against transferring (especially prescription) medication from the labelled bottles they come in to other, unlabelled containers.
What this essentially means is that just about every person who has to take medications at various times during the day is a potential felon if they have one of those mtwtfss boxes that keeps pills separated by day so they can make sure they take their medication properly. This is one of the (allegedly) unintentional consequences of our insane war on drugs. The government needs to be informed that you simply can't legislate everything.
Indeed, unfortunately, much of the populace is distracted and they do not realize the vast extant of the problem.