And if you are inexperienced and don't shoot often then I would never recommend a caliber as big as either of these because you won't be able to hit the broad side of a barn unless its pure luck.
I sometimes use my 357 Revolver with 38+P in Self Defense Round as a Carry Gun. Other times a 1911 45 ACP Cocked and Locked.
I take my wife and daughter out shooting occasionally. They love the heft of a .357 tempered using .38spc.
Just every once in a while I’ll slip in a .357 with the .38’s.
I just tell them I’m checking their grip, but it always makes them jump and I get a dirty look.