[Magnum44]

My wife really likes the Glocks and with their safeties she can keep one in the pipe.

Just a little confused by your statement. For self defense you would always want one in the pipe (no time to rack slide in most cases), but the Glock only has the safe trigger, so you do have to handle appropriately. Recommend not in a pocket or purse, but rather a hard holster with trigger and guard completely covered. What other safeties were you referring too?

[ImJustAnotherOkie]

Exactly like a revolver. Racking a slide and clicking off a safety are both non-starters, especially with the gentler sex. Most of them tolerate guns but don't like them and they don't get as much practice time. That is the key point I always liked about revolvers is just pull the trigger. I believe Glock's safety system may be safer than a simple revolver.