I don’t think the Founding Fathers would have been perplexed at all. They resisted tyranny, and wrote a Constitution that guaranteed freedom to all. They spoke of Unalienable Rights, no federal interference in religion, and standing up to tyranny. They would have been relieved to finally see someone get it.
I have to think that the notion of the third equal branch of government’s reigning supreme over the US Congress (Defense of marriage act) and the state of Kentucky, to the point of robbing this woman of liberty and her own 1st amendment rights would seem absurd to them.