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To: MD Expat in PA

23andMe is basically a data collection thing. When they send you the kit (for which you have paid something), they then ask you a million genetic research questions - about your family, your body, your health, etc. - before you can even go ahead.

Also, if you’re a woman, you can’t get a very clear reading on the genetic background since you’re missing part of it. If you have a brother, have him do it.

Basically, I’d say that if you want to do it, it will give you something although not very much if you’re a woman, but refuse to fill out their forms unless you really like that sort of thing.


53 posted on 01/11/2014 4:34:19 PM PST by livius
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To: livius
Also, if you’re a woman, you can’t get a very clear reading on the genetic background since you’re missing part of it. If you have a brother, have him do it.

I think perhaps you are partly confused on this.

Females, as well as males, can discover their ancient maternal lineage through DNA testing. Because a father's mitochondrial DNA (mtDNA) is destroyed at fertilization, a child inherits only the mother's mitochondrial DNA, thus preserving the maternal link to the ancient past. Due to this unique inheritance pattern, both males and females may directly contribute a DNA sample for testing the maternal lineage.

http://ldna.ancestry.com/learnMoreMaternal.aspx

A male providing his Y-chromosome sample also represents the DNA of his father, paternal grandfather, and so on up the paternal line. Y-chromosome results are generally identical throughout the paternal line. But because mutations do occur, it is possible for a son's results to be slightly different from his father's or his brother's.

Women, in spite of not carrying a Y-chromosome, can still trace their paternal lineage. Using a DNA sample provided by a brother, father, or another paternal relative (for example, a male cousin) a woman can treat these Y results as if they were her own.

http://ldna.ancestry.com/learnMorePaternal.aspx

So basically a woman can trace her material ancestry through her own DNA sample without having to also submit the DNA of a male sibling or paternal relative but if she wants to trace her paternal lineage she would have to use the DNA sample provided by a full brother, her father, or another paternal relative (for example, a male cousin).

So if I do decide to get a 23andMe test, I’d probably offer and pay for my brother to get one too in order to get a more complete picture.

71 posted on 01/15/2014 5:42:54 PM PST by MD Expat in PA
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