Both New York and Virginia explicitly retained the right to secede from the USA through specific language in their conditional ratification of the Constitution.
Thank you Patrick Henry.
Oh, and if I’m not mistaken Wyoming filed an amacus brief in the Heller case which basically said if the ruling went against Heller, Wyoming considered it a breach of contract with the federal government...secession.
Signing statements to the ratification process don’t carry the weight of law. They may have been a reassurance to folks but they aren’t enforceable.