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Keyword: parthenolide

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  • A potential active ingredient for nerve regeneration (Parthenolide, from Feverfew)

    03/09/2024 5:12:56 PM PST · by ConservativeMind · 18 replies
    Medical Xpress / Uniklinik Köln / The Journal of Neuroscience ^ | Match 4, 2024 | Christoph Wanko / Philipp Gobrecht et al
    Nerve fibers (axons) transmit brain and spinal cord signals through nerves to target muscles or skin, and vice versa. Damage to these fibers thus leads to a disruption of connections and, consequently, to paralysis or numbness. The chances of recovery depend mainly on the speed at which the severed fibers regenerate as this process is time-limited, so usually only short distances can be overcome. Consequently, nerve injuries in the legs and arms often lead to permanent damage, which later may be accompanied by neuropathic pain. Therefore, a key therapeutic goal of research is the development of therapies to accelerate nerve...