https://freerepublic.com/tag/myeloid/ en-us Thu, 20 May 2021 13:43:49 GMT Focus Forum 15 https://freerepublic.com/focus/f-chat/3960880/posts Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease’s high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) stem and progenitor cells (HSPC). A study released in STEM CELLS adds to this extent of knowledge by showing how secreted cell factors, in particular a protein called transforming growth factor beta 1 (TGFβ1), leads to a breakdown in the production of healthy blood cells (a process called hematopoiesis) in humans. The study’s findings indicate that blocking TGFβ1 could improve hematopoiesis in AML patients. Although AML... https://scitechdaily.com https://freerepublic.com/focus/f-chat/3960880/posts#comment Thu, 20 May 2021 13:43:49 GMT