https://freerepublic.com/tag/monoclonalantibody/ en-us Thu, 5 Dec 2024 03:52:46 GMT Focus Forum 15 https://freerepublic.com/focus/f-chat/4282602/posts Head and neck cancers are the seventh most common type of cancer worldwide. The chemotherapy drug cisplatin is the gold standard for treating these malignancies. However, more than 30% of patients, including some older adults and those with pre-existing kidney disease or hearing loss, cannot take cisplatin due to severe side effects. The monoclonal antibody cetuximab, while not as effective as cisplatin, is often used as an alternative in these patients. Durvalumab, an immune checkpoint inhibitor, has shown promise for treating a wide range of cancers, and has been proposed as a potentially safer and more effective option than cetuximab,... Medical Xpress / University of California - San Diego / The Lancet Oncology https://freerepublic.com/focus/f-chat/4282602/posts#comment Thu, 5 Dec 2024 03:52:46 GMT https://freerepublic.com/focus/f-chat/4183363/posts Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers. The multicenter, randomized Phase II NeoCOAST clinical trial evaluated neoadjuvant durvalumab alone and in combination with each of the following novel immunotherapies: the anti-CD73 monoclonal antibody oleclumab, the anti-NKG2A monoclonal antibody monalizumab, and the anti-STAT3 antisense oligonucleotide danvatirsen. The NeoCOAST study enrolled 84 patients with untreated, resectable (>2cm), stage I-IIIA NSCLC. Eighty-three patients received one 28-day cycle of neoadjuvant durvalumab alone or combined with another therapy. The investigators assessed pathological complete... Medical Xpress / University of Texas M. D. Anderson Cancer Center / Cancer Discovery https://freerepublic.com/focus/f-chat/4183363/posts#comment Tue, 19 Sep 2023 02:06:01 GMT https://freerepublic.com/focus/f-chat/4036087/posts Indiana-based Eli Lilly and Company reported on February 3, 2022, it recently submitted a request for Emergency Use Authorization to the U.S. FDA for bebtelovimab, an investigational anti-SARS-CoV-2 Monoclonal Antibody (mAbs). Bebtelovimab, which neutralizes the SARS-CoV-2 spike glycoprotein receptor-binding domain-specific antibody, is being evaluated to treat mild-to-moderate COVID-19 in adults and pediatric patients 12 years of age and older. Lilly's recent financial disclosure says 'authentic virus analysis of bebtelovimab confirmed earlier pseudovirus findings, which demonstrated bebtelovimab neutralizes coronavirus variants of concern, including Omicron.' The U.S. NIH's OpenData Portal Therapeutic Activity Explorer separately confirmed bebtelovimab's effectiveness against Omicron as of February... precisionvaccinations.com https://freerepublic.com/focus/f-chat/4036087/posts#comment Mon, 7 Feb 2022 02:24:57 GMT https://freerepublic.com/focus/f-news/4007050/posts Joe Rogan and Michael Malice discussed last week why the corporate press continues to dismiss ways doctors can treat Covid-19 aside from vaccination. Rogan said that Dr. Pierre Kory from the Front Line Critical Care Covid group treated him and hundreds of members of Congress with monoclonal antibodies, prednisone, z-pak, NAD, vitamins, and ivermectin. ... 200 Congress people have been treated with Ivermectin for Covid. .. Before there were vaccines, this was a common off-label treatment for Covid. "I do not know the motivation for demonizing this particular medication .. But I would imagine some of it has to do... Real Clear Politics https://freerepublic.com/focus/f-news/4007050/posts#comment Tue, 26 Oct 2021 23:09:20 GMT https://freerepublic.com/focus/f-news/4012932/posts GRAND RAPIDS, Mich. (WOOD) — The start of firearm deer season in Michigan is something many hunters look forward to all year, but new research shows that trekking into the woods could bring you closer to COVID-19 than you might expect. A study from the U.S. Department of Agriculture found COVID-19 antibodies in two-thirds of a white-tailed deer sample tested in Michigan. The USDA’s Animal and Plant Health Inspection Service took 113 samples from white-tailed deer between January 2020 and March 2021 and found that 67% of them had COVID-19 antibodies. WOOD TV Grand Rapids https://freerepublic.com/focus/f-news/4012932/posts#comment Mon, 15 Nov 2021 19:01:58 GMT https://freerepublic.com/focus/f-news/3892177/posts Uninformed commentary has emerged this morning stating that President Trump has received a medication created with the use of human embryonic stem cells. CLI has reviewed the published information and our conclusion is straightforward: The president was not given any medicines to treat COVID-19 that involved the destruction of human life. No human embryonic stem cells or human fetal tissue were used to produce the treatments President Trump received–period. Let’s look at the facts. The Regeneron therapy given to the president was made in Velocimmune humanized mice, a novel platform that uses genetically modified mouse embryonic stem (ES) cells to... LifeSiteNews https://freerepublic.com/focus/f-news/3892177/posts#comment Fri, 9 Oct 2020 17:41:46 GMT https://freerepublic.com/focus/f-chat/4026656/posts Jeff Kuhner of the Kuhner Report is recovering from Covid (Delta) Fill in Sandy Shack updated his listeners. He will return on Monday January 10th, 2022Sandy also noted he was treated with Ivermectin and MonoClonal Antibodies. You Tube, originally broadcasted on AM 680 WRKO, Boston https://freerepublic.com/focus/f-chat/4026656/posts#comment Tue, 4 Jan 2022 15:38:45 GMT https://freerepublic.com/focus/f-news/4025517/posts Dr. Ron Elfenbein called the pause in some antibody treatments the 'height of bureaucratic arrogance'.. A doctor in Maryland said he had to cancel potentially life-saving monoclonal antibody infusions for about 250 people over the last week after the federal government stopped distributing treatments made by Regeneron and Eli Lilly because they aren't effective against omicron, even though the delta variant, which the drugs are effective at treating, was still dominant at the time. The Office of the Assistant Secretary for Preparedness and Response halted the allocation of those two antibody treatments last Thursday amid the rise of omicron, which... Fox News https://freerepublic.com/focus/f-news/4025517/posts#comment Fri, 31 Dec 2021 00:44:33 GMT https://freerepublic.com/focus/f-news/4024840/posts Sen. Rand Paul pinned blame for thousands of monthly coronavirus deaths on Dr. Anthony Fauci over his bias toward vaccines. "I would venture to say that thousands of people die in our country every month now from COVID because [Fauci’s] deemphasized the idea that there are therapeutics," Paul, who is also a physician, said in an interview on the Ron Paul Liberty Report published Monday. Paul explained that Fauci has a long history of a "bias" toward vaccines, stretching back to his work on AIDS. "I think Fauci is of the philosophy that vaccines are incredibly successful and are the... Fox News https://freerepublic.com/focus/f-news/4024840/posts#comment Tue, 28 Dec 2021 16:39:02 GMT https://freerepublic.com/focus/f-news/4022899/posts Former President Donald Trump urged his supporters on Sunday to get a booster shot of the COVID-19 vaccine to protect themselves against the Omicron variant, telling them they're "playing right into their hands" by doubting the vaccines. ... "Look, we did something that was historic," he said. "We saved tens of millions of lives worldwide. We, together, all of us, not me." ... "I think this would have been the Spanish Flu of 1917, where up to 100 million people died," he said. "This was going to ravage the country far beyond what it is right now." Business Insider https://freerepublic.com/focus/f-news/4022899/posts#comment Mon, 20 Dec 2021 19:33:06 GMT https://freerepublic.com/focus/f-chat/4023384/posts Federal supply of the one monoclonal antibody treatment that has proven effective is now "limited," with more doses expected in January, a Health and Human Services spokesperson said. Major hospitals in the New York region say they have stopped using monoclonal antibody therapies because they have run out of the one treatment that appears to be effective against the omicron variant of the coronavirus, leaving doctors without a vital tool to treat severely ill Covid-19 patients. New York University and Valley Health System in northern New Jersey notified doctors Sunday... Meanwhile, Mount Sinai Health System in New York said it... NBC https://freerepublic.com/focus/f-chat/4023384/posts#comment Wed, 22 Dec 2021 08:43:55 GMT https://freerepublic.com/focus/f-bloggers/4022587/posts Daniel Horowitz - Persecution of the Unvaccinated Rumble https://freerepublic.com/focus/f-bloggers/4022587/posts#comment Sun, 19 Dec 2021 16:01:09 GMT https://freerepublic.com/focus/f-chat/4020983/posts Last week, the World Tribune published an article revealing information that indicates the WHO likely knew ivermectin was effective for months, but blocked its use, all for Big Pharma. Dr. Andrew Hill, a senior visiting research fellow in pharmacology at Liverpool University, adviser to the Gates Foundation, and researcher for the WHO, was tasked with conducting an ivermectin trial for the WHO. Based on his preliminary findings, Hill testified enthusiastically about the use of ivermectin before the NIH COVID-19 Treatment Guidelines Panel on Jan. 6, 2021. But then he suddenly changed course and published a study dinging the drug’s efficacy... The Blaze https://freerepublic.com/focus/f-chat/4020983/posts#comment Tue, 14 Dec 2021 02:28:44 GMT https://freerepublic.com/focus/f-bloggers/4012502/posts Monoclonal Antibodies are perhaps the most effective treatment for hospitalized cases of Covid. Getting it can easily make the difference between life and death, or a lifetime of complications versus a shorter stay. This is the treatment the Florida governor worked so hard to make available, and which Biden threatened to ration away from Red States. Watch this short video to hear hospital staff explain that this treatment is systematically denied to white people without comorbidities, but is consistently given to blacks and hispanics in similar condition. By policy. Systematically. twitter https://freerepublic.com/focus/f-bloggers/4012502/posts#comment Sat, 13 Nov 2021 23:00:41 GMT https://freerepublic.com/focus/f-chat/4006662/posts Beloved young relative has covid. There is no Regeneron in the state. Offered Sotromab. Feedback? Never heard of it. https://freerepublic.com/focus/f-chat/4006662/posts#comment Mon, 25 Oct 2021 20:45:18 GMT https://freerepublic.com/focus/f-chat/4000850/posts AstraZeneca, the drugmaker that developed one of the first COVID-19 vaccines, has asked the U.S. Food and Drug Administration to authorize the emergency use of a first-of-a-kind antibody treatment to prevent the disease. The Anglo-Swedish company said Tuesday that the treatment, known as AZD7442, would be the first long-acting antibody combination to receive an emergency authorization for COVID-19 prevention. If authorized, the drug would likely be limited to people with compromised immune systems who don’t get sufficient protection from vaccination. “First and foremost we want to protect those vulnerable populations that haven’t been adequately protected by the vaccine,” said Menelas... Associated Press https://freerepublic.com/focus/f-chat/4000850/posts#comment Tue, 5 Oct 2021 16:55:40 GMT https://freerepublic.com/focus/f-news/3995238/posts President Joe Biden’s administration may reportedly implement a new policy to limit the number of antibody treatments shipped to some states with high demands for it, possibly curtailing the medicine for states with Republican governors, Politico reports. According to Politico, the Biden administration is “imposing new limits on states’ ability to access to Covid-19 antibody treatments amid rising demand from GOP governors who have relied on the drug as a primary weapon against the virus.”: Federal health officials plan to allocate specific amounts to each state under the new approach, in an effort to more evenly distribute the 150,000 doses... Breitbart https://freerepublic.com/focus/f-news/3995238/posts#comment Wed, 15 Sep 2021 20:31:42 GMT https://freerepublic.com/focus/f-chat/3991066/posts More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus. However, questions persist regarding the duration of the immune response or the need for a booster. Also, controlling the pandemic means vaccinating billions of people. Yet manufacturing sufficient doses to protect the entire world population represents a considerable challenge. That is why vaccine research is still ongoing in order to develop additional candidate vaccines and to continue to meet these various challenges. Researchers from... https://scitechdaily.com https://freerepublic.com/focus/f-chat/3991066/posts#comment Wed, 1 Sep 2021 18:26:19 GMT https://freerepublic.com/focus/f-news/3996630/posts Florida Governor Ron DeSantis said that he was “very, very concerned” with Democrat President Joe Biden’s decision to restrict the distribution of monoclonal antibodies to states amid a surge in demand by states in the South. “Just last week on September 9th, President Joe Biden said that his administration would be increasing shipments of monoclonal antibodies in September by 50%, and yet on September 13th, HHS announced that it was seizing control of the monoclonal antibody supply and that it would control distribution, and then on September 14th, the announcement was more than 50% of the monoclonal antibodies that had... Daily Wire https://freerepublic.com/focus/f-news/3996630/posts#comment Mon, 20 Sep 2021 18:05:58 GMT https://freerepublic.com/focus/f-news/3995990/posts A spokesperson for Florida Gov. Ron DeSantis’s office said that more than half of those who are seeking monoclonal antibody treatment in the south of Florida are “fully vaccinated” individuals amid supply issues.“More than half the patients getting the monoclonal antibody treatment in south Florida are fully vaccinated,” DeSantis spokeswoman Christina Pushaw wrote in response to a comment on Twitter that suggested that only unvaccinated people are the reason why there is a significant demand for monoclonal antibodies.Florida, she wrote hours earlier, “is above average in vaccination rate” and that “more than half of the patients in south Florida getting... Epoch Times https://freerepublic.com/focus/f-news/3995990/posts#comment Sat, 18 Sep 2021 02:02:49 GMT https://freerepublic.com/focus/f-chat/3991187/posts Huntsville Memorial Hospital is the latest to start offering COVID-19 monoclonal antibody infusion treatments. As the number of COVID-19 hospitalizations continues to rise across the state, more treatments and resources are becoming available for those who contract the virus. Dr. Sujesh Pillai is the chief of staff for Huntsville Memorial. He says they’ve administered a little over 50 infusions in the last two weeks, and only one person had to be admitted to the hospital. “When you get the infusion treatment, it’s a one-hour IV infusion that we do in the hospital. You’re not admitted. You go home right after... KBTX https://freerepublic.com/focus/f-chat/3991187/posts#comment Thu, 2 Sep 2021 03:20:05 GMT https://freerepublic.com/focus/f-chat/3991134/posts Podcast host Joe Rogan — who has openly criticized the need for COVID-19 vaccines — has been diagnosed with the coronavirus. The 54-year-old announcer revealed he contracted the coronavirus in a recent social media post. “I GOT COVID. My apologies, but we have to move the Nashville show to Sunday, October 24. Much love to you all,” he wrote alongside a video of himself explaining his situation. In the clip, Rogan said felt “very weary,” adding, “I had a headache, and I just felt just run down” after several tour dates in Florida. He added that he was quarantined from... NY Post https://freerepublic.com/focus/f-chat/3991134/posts#comment Wed, 1 Sep 2021 23:18:48 GMT https://freerepublic.com/focus/f-chat/3989077/posts Sotrovimab, the newest antibody therapy, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists from across the nation discovered a natural antibody (in the blood of a SARS survivor, back in 2003) that has remarkable breadth and efficacy. Experiments showed that this antibody, called S309, neutralizes all known SARS-CoV-2 strains – including newly emerged mutants that can now “escape” from previous antibody therapies – as well as the closely related original SARS-CoV virus. Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), used beamlines at the ALS and... Sci Tech Daily https://freerepublic.com/focus/f-chat/3989077/posts#comment Thu, 26 Aug 2021 16:50:06 GMT https://freerepublic.com/focus/f-news/3987982/posts A new monoclonal antibody treatment has been found to protect chronically ill adults from developing COVID-19. The Phase 3 trial results suggest the novel antibody cocktail, delivered by intramuscular injection, could offer up to 12 months protection. New Atlas https://freerepublic.com/focus/f-news/3987982/posts#comment Mon, 23 Aug 2021 15:21:54 GMT https://freerepublic.com/focus/f-chat/3987167/posts Graphical abstract. Credit: DOI: 10.1016/j.cell.2021.07.033 A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that in laboratory and animal studies prevented infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus (EEEV). EEEV, which infects the central nervous system of humans, horses and other animals, is the most virulent encephalitic alphavirus. Although only a few human cases are reported annually in the United States, the fatality rate exceeds 30%, and there are no approved vaccines or antiviral drugs to treat it. These results, reported in the current issue of the journal Cell, represent new... https://phys.org https://freerepublic.com/focus/f-chat/3987167/posts#comment Fri, 20 Aug 2021 19:31:14 GMT