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  • Two new drugs finally hit ‘undruggable’ cancer target, providing hope for treatments

    11/21/2019 12:48:02 PM PST · by Red Badger · 4 replies
    www.sciencemag.org ^ | By Jocelyn Kaiser Oct. 30, 2019 , 2:00 PM
    Cancer researchers are making progress toward a goal that has eluded them for more than 30 years: shrinking tumors by shutting off a protein called KRAS that drives growth in many cancer types. A new type of drug aimed at KRAS made tumors disappear in mice and shrank tumors in lung cancer patients, two companies report in papers published this week. It’s not yet clear whether the drugs will extend patients’ lives, but the results are generating a wave of excitement. And one company, Amgen, reports an unexpected bonus: Its drug also appears to stimulate the immune system to attack...