Skeletal muscle plays an extremely important role in supporting movement and energy metabolism. However, its function can be impaired by aging and muscle-related diseases, resulting in decreased endurance or strength of skeletal muscle. Skeletal muscle function decreases with the increase of age or the development of disease. After the age of 30, muscle mass decreases by about 3%–8% every decade. Duchenne muscular dystrophy (DMD), a common muscular dystrophy in children, causes proximal muscle weakness and calf hypertrophy, eventually leading to degeneration of skeletal and cardiac muscle. Therefore, healthy skeletal muscle is very important to the body. However, skeletal muscle is...