My level of sleep definitely affects my kidneys. I go the the bathroom less on the sleep apnea machine but I haven’t been using it lately.
Also if I knock myself out. I have been experimenting with a cough suppressant for histamine intolerance after reading an article by a guy researching low dose naltrexone. So for example..half a tablet of the DM product last night let me sleep through the night with no bathroom break and I had less itching. Same happens with less than 5 MG of LDN