Some options:
- Parliamentary point of order that supermajority for up-or-down advice and consent is unconstitutional (the so-called "nuclear" option)
- S-138, a bill to change the rules of the Senate, whereby the threshold for cloture, for advice and consent, is lowered in successive votes until a simple majority suffices
- Change the Senate rules at the start of the next Congress
- Take a case to SCOTUS (stronger if the President joins, but politically dangerous)
- Provoke public pressure to prevail on the sensibilities of the recalitrant DEM Senators