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Parkinson's dyskinesia mechanism explained
05/04/2020 5:45:36 AM PDT · by zeestephen · 7 replies
Science Daily ^ | 01 May 2020
Many people with Parkinson's disease eventually develop debilitating movements called dyskinesia, a side effect of their much-needed dopamine replacement medication. The mechanism underlying this unwanted side effect has been unknown, until now. An international collaboration led by Scripps Research, Florida has found a key cause, and with it, potentially, a new route to providing relief.

Ozzy Osbourne Diagnosed with Parkinson's Disease
01/22/2020 7:39:19 PM PST · by wastedyears · 70 replies ^ | 1/21/2020 | Philip Trapp
On Tuesday (Jan. 21), Ozzy Osbourne shocked the rock world by revealing his recent diagnosis with Parkinson's disease, a long-term degenerative disorder of the central nervous system. The news comes after a string of health woes throughout 2019 pushed back the singer's tour dates across the world.

Waking up dormant dopaminergic neurons to reverse Parkinson's disease (Reverse early Parkinson’s)
01/09/2020 9:06:28 PM PST · by ConservativeMind · 8 replies
Institute for Basic Science ^ | January 9, 2020 | Many
As many as seven to 10 million people in the world are thought to live with Parkinson's disease (PD). Current medical treatments for PD rely on alleviating PD symptoms with little efforts to explore ways to reverse the symptoms. It is firmly believed that abnormal movements of PD begin in the brain where the production of dopamine, a neurotransmitter for movement control, is irreversibly impaired. Currently, L-DOPA, a potent PD medication is mainly prescribed to replenish dopamine in the deprived brain. However, such treatment is symptomatic, not disease-modifying therapy. The researchers reported that the symptoms of PD begin when dopaminergic...

Parkinson's Patients are Mysteriously Losing the Ability to Swim After Treatment
11/27/2019 6:51:49 PM PST · by BenLurkin · 22 replies
Discover Magazine ^ | November 27, 2019 1:00 PM | By Jennifer Walter
For Parkinson’s patients, deep brain stimulation (DBS) can help control a number of neurological symptoms, like muscle spasms and stiffness. But one weird side effect has surfaced in a string of case studies: Some patients, no matter how good their motor skills, lose their ability to swim after the procedure. Researchers from the University of Zürich in Switzerland published a report today in Neurology identifying nine cases where patients couldn’t stay afloat after DBS. And these people weren’t water-shy, first time doggie paddlers — two of the cases involved former competitive swimmers. And, researchers report, the entire cohort had had...

Japan team transplants stem cells into brain to treat Parkinson's
11/10/2018 6:36:21 PM PST · by Olog-hai · 23 replies
Agence France-Presse ^ | 9 Nov 2018
Japanese researchers said Friday they have transplanted stem cells into the brain of a patient in the first stage of an innovative trial to cure Parkinson’s disease. The research team at Kyoto University injected induced Pluripotent Stem (iPS) cells — which have the potential to develop into any cell in the body — into the brain of a male patient in his fifties, the university said in a press release. The man was stable after the operation, which was performed last month, and he will now be monitored for two years, the university added. The researchers injected 2.4 million iPS...

Brain implants used to treat Parkinson's can be hacked and used to control people, scientists warn
11/01/2018 3:23:13 AM PDT · by SkyPilot · 32 replies
Telegraph ^ | 31 Oct 18 | Natasha Bernal
Brain implants used to treat Parkinson's disease could be hacked by cyber attackers and used to control people, scientists have claimed. A report by the Oxford Functional Neurosurgery Group and cyber security company Kaspersky claims that people's memories could be exploited by hackers and has called on cyber security companies, manufacturers and healthcare companies to develop new technology to stop them. Academics have previously warned that brain implants could prevent patients from "speaking or moving, cause irreversible damage to their brain, or even worse, be life-threatening". They claimed that hackers could overload or disable the system, and could damage...

Alan Alda reveals he has Parkinson's disease: "I'm not angry"
07/31/2018 11:33:42 AM PDT · by 2ndDivisionVet · 33 replies
CBS News ^ | July 31, 2018 | Jessica Kegu
Alan Alda has Parkinson's disease. In an appearance on "CBS This Morning" Tuesday, the award-winning actor, best known for his relatable portrayal of Army Capt. "Hawkeye" Pierce in the TV series "M*A*S*H," revealed he was diagnosed three-and-a-half years ago. "I've had a full life since then," he said. "I've acted, I've given talks, I help at the Alda Center for Communicating Science at Stony Brook. I started this new podcast. And I noticed that – I had been on television a lot in the last couple of weeks talking about the new podcast – and I could see my thumb...

Actor Alan Alda says he has Parkinson's disease
07/31/2018 6:33:22 AM PDT · by SMGFan · 83 replies
ABC ^ | July 31, 2018
Alan Alda announced Tuesday that he has Parkinson's disease. Alda -- the Emmy award-winning actor who starred in the long-running series "M.A.S.H." as beloved combat doctor Hawkeye Pierce -- said in an interview on "CBS This Morning" that he was diagnosed with Parkinson's in 2015.

Masa Saito passes away after long battle with Parkinson's disease (pro wrestler Mr. Saito)
07/16/2018 10:12:47 AM PDT · by EveningStar · 8 replies
Wrestling Observer Online / Figure Four ^ | July 16, 2017 | Dave Meltzer
Masanori Saito, a former Olympian as an amateur wrestler and Hall of Famer as a pro, passed away on Saturday after a long battle with Parkinson's disease. Saito was 76. Saito had the most successful long-term career of any Japanese native on the American scene, being a championship-level wrestler in multiple territories from 1968 to 1990. While Giant Baba in the 60s, Great Muta, and now Shinsuke Nakamura were as big or bigger stars, Saito spent the majority of his career in the United States as opposed to a brief version, and was always a headliner as a former Olympian...

Dr. Ted Noel: Hillary Clinton Falls Again ... and Again ... (Parkinson's disease confirmed)
03/18/2018 3:46:14 PM PDT · by Zakeet · 114 replies
YouTube ^ | March 13, 2018 | Dr. Ted Noel
Dr. Noel is the physician who discussed Hillary's health issues during the campaign and formed a medical opinion that she was most likely suffering from Parkinson's disease. In his new video, he analyzes her latest "event" in India on a frame by frame basis and concludes that it is more evidence that his original call was correct. In case you are interested, the original videos where Dr. Noel discussed Hillary's problems are: Hillary Clinton's Illness Revealed (4.9 million views BREAKING: Dr. Ted Noel Reveals Hillary's Major New Parkinson's Health Warnings That Could End Her Hillary Falls Again

Neil Diamond Announces Retirement From Concert Touring After Parkinson's Diagnosis
01/23/2018 12:46:47 AM PST · by nickcarraway · 47 replies
Hollywood Reporter ^ | 1/22/2018 | Rania Aniftos
The icon, who will be presented with a lifetime achievement at the Grammys on Sunday, has cancelled the third leg of his world tour on the advice of his doctor. Neil Diamond has officially announced his retirement from touring due to his recent Parkinson’s diagnosis. The third leg of his 50th Anniversary tour, which was set to launch in March across Australia and New Zealand, has been cancelled as was medically recommended by his doctor. Fans who already purchased tickets will be refunded in full. “I plan to remain active in writing, recording and other projects for a long time...

Pfizer Ends Hunt for Drugs to Treat Alzheimer's and Parkinson's
01/08/2018 1:02:48 PM PST · by sodpoodle · 32 replies
Fox Business ^ | 01/06/2018 | Jonathan Rockoff
Pfizer Inc. said Saturday it will stop trying to discover new drugs for Alzheimer's disease and Parkinson's disease, abandoning costly but futile efforts to find effective treatments for the disorders. The cutback will result in layoffs of 300 employees in Cambridge and Andover in Massachusetts and in Groton, Conn., over several months, according to a company statement. The restructuring won't affect later-stage drug development for pain treatments Lyrica and tanezumab, or research into drugs for rare neurological diseases, Pfizer said. The company plans to use the savings to fund drug R&D in other areas. "This was an exercise to reallocate...

New findings point to potential therapy for Parkinson's Disease
12/19/2017 8:53:25 AM PST · by Red Badger · 3 replies ^ | December 19, 2017 | by Anna Williams, Northwestern University
Partial inhibition of the interaction between calcineurin and FKBP12, with low doses of the FDA-approved compound Tacrolimus, protect neurons against the toxic effects of a-synuclein, a protein critically implicated in Parkinson’s disease. Credit: Northwestern University ======================================== A new study, published in Proceedings of the National Academy of Sciences (PNAS), sheds light on a mechanism underlying Parkinson's disease and suggests that Tacrolimus—an existing drug that targets the toxic protein interaction explored in the study—could be used as a novel treatment. Gabriela Caraveo Piso, Ph.D., assistant professor of Neurology in the Division of Movement Disorders, was the first and corresponding author of...

Jesse Jackson diagnosed with Parkinson's disease
11/17/2017 9:25:04 AM PST · by simpson96 · 86 replies
CNN ^ | 11/17/2017 | Susan Scutti
(CNN) — Civil rights activist the Rev. Jesse Jackson said Friday that he has been diagnosed with Parkinson's disease. A neurological disorder with no cure, Parkinson's can cause tremors, stiffness and difficulty balancing, walking and coordinating movement. "My family and I began to notice changes about three years ago," Jackson wrote in a statement. "After a battery of tests, my physicians identified the issue as Parkinson's disease, a disease that bested my father." Jackson added that "recognition of the effects of this disease on me has been painful." He also said he sees his diagnosis as "a signal that I...

PRAYER REQUEST!! Police, family seek help in locating missing man with Parkinson's, dementia
10/03/2017 11:34:44 AM PDT · by US Navy Vet · 14 replies
KETV Omaha ^ | by Maggie Cunningham
TEKAMAH, Neb. — A Tekamah man went missing early Monday morning and family members said they have been searching for him since 9 a.m. Police were notified around 11 a.m. that Rolland Metz, 75, was gone from the Tekamah Health and Rehabilitation Nursing Home located near M and 9th streets. Advertisement Family said Metz has Parkinson's and dementia has missed two rounds of medication already and is deemed incompetent. They said Metz was last seen wearing blue jeans, black tennis shoes, a black vest puffy, a cream button up long-sleeved shirt and a blue ball cap. Anyone with information is...

Parasite Linked with Alzheimer's And Parkinson's Diseases, Epilepsy, and Cancer
09/14/2017 5:55:32 AM PDT · by Enlightened1 · 48 replies
Genetic Engineering and Biotechnology News ^ | 09/13/17
About a third of the world’s population is chronically infected with the protozoan parasite Toxoplasma gondii. Data from the U.S. Centers for Disease Control and Prevention (CDC) suggest that about 11% of the U.S. population aged 6 years and over is infected with the parasite, while in other countries the infection rate has been shown to be up to 95%. Researchers from 16 institutions across the U.S., Canada, England, Scotland, and Australia have now analyzed genetic, transcriptomic, and proteomic data from infected individuals, and from studies in cell cultures, to link T. gondii infection with a number of brain disorders,...

Brain cell therapy 'promising' for Parkinson's disease (hope for Hillary alert)
04/11/2017 12:46:29 AM PDT · by Zakeet · 8 replies
BBC ^ | April 11, 2017
Scientists believe they have found a way to treat and perhaps reverse Parkinson's disease, by making replacement cells to mend the damaged brain. They say human brain cells can be coaxed to take over the job of the ones that are destroyed in Parkinson's. Tests in mice with Parkinson-like symptoms showed that the therapy appeared to ease the condition. Many more studies are needed before similar tests can begin in people. Experts say the research published in Nature Biotechnology is hugely promising, although at a very early stage.

Key cause of Parkinson's disease can be treated
12/01/2016 2:24:42 PM PST · by Red Badger · 31 replies ^ | December 1, 2016 | Provided by: University of New South Wales
A new Australian study that models the early stages of Parkinson's disease has given researchers insight into its causes and a possible treatment. "We've shown how inflammation within the brain is related to the development of Parkinson's disease, and we've identified a potential mechanism that can prevent this inflammation," says lead author Dr Nic Dzamko, a NHMRC CJ Martin Fellowship holder in the Faculty of Medicine at UNSW in Sydney. "This is the result of four years' worth of work, and we're really excited by the outcomes. It offers hope and introduces a new target for therapeutic research, which we're...

Hillary Clinton Parkinson's - Debate 3 Analysis (Dr. Ted Noel)
10/25/2016 4:45:32 PM PDT · by Meet the New Boss · 18 replies
Webtech Vidzette youtube ^ | 24 Oct 2016 | Dr. Ted Noel
Dr. Ted Noel looks at footage of the third debate and the Alfred Smith Dinner in light of possible Parkinson's symptons. See the footage at 2:33 for serious eye-crossing events by Hillary at the Alfred Smith dinner. Hillary Parkinson's symptoms

10/22/2016 10:07:20 AM PDT · by Jeff Chandler · 51 replies
Headline of the Day ^ | 10-22-2016
Headline of the Day Poll When will Hillary's Parkinson's become unmanageable? Early in her presidencyIn her second termAfter she leaves office VoteView Results Read more:
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