Thanks for addressing the nebulosity and inanity of my comment about multiple stuff going wrong.
The tire blew upon inflation, hydraulics failed.. damaged tile(s) allowed wing burn-thru.. a key sensor(s) failed for as yet to be determined reason(s).. temps increased in the left wing wheel well area ???
Pick one or all of the above. Was the foam the precipitating event during the launch?
The foam was not the precipitating cause of this disaster. To effectively rotate the shuttle off of its normal descent axis takes more then a few tiles falling off and would have been noticed at the launch.
Something internal to the shuttle failed, at a minimum in the elevon structure.