Apparently the Soviets did a lot of research on recombinants of smallpox and have weaponized extremely lethal variants. Whether the "normal" vaccinia vaccination would cover the new variants is probably questionable because the variants are re-engineered with other diseases, such as ebola. Who knows if the immune antibodies will react to these different threats, who no doubt have different signatures?
There is a discussion of it in this article THE BIOWEAPONEERS.