A clean room environment big enough to: allow two or three people to work immediately next to the bomb without hitting each other; ensure that the bomb is not exposed to anything but extremely dehumidified air (lithium hydride/deuteride/tritide is amazingly hygroscopic); ensure that all workers are on supplied air (no exhaled moisture hitting the lithium tritide); and ensure that the facility is shielded well enough so that there are no detectable gamma and neutron emissions (gamma shielding is a fairish amount of lead; neutron shielding is LOTS of polystyrene foam) to alert NEST. You'd need to make very noticeable modifications to a largish residential home at a minimum.