Cancer breakthrough stuns scientific world

itechnology ^ | September 05 2002 at 08:26PM | Steve Connor

[TIGHTEN]

People that contracted Aids have just as much rights as any cancer victim-are you for real? And I'm not a relative of someone with Aids but rather someone who recently buried their brother from lung, brain, throat,bladder and skin cancer. I suppose your thinking would also apply to babies and children who have been infected with Aids from blood transfusions. Let's hope you or nobody you love is ever infected with Aids. I'm sure you'd be dancing to a different tune "chachacha" and demand that your DECENT loved one had earned their opportunity to be in line for the treatment. Nobody should be penalized for the way they got Aids-how sad it is to know that someone would feel that way and mean it. There's no "waltzing" around it "chachacha" your mixed up, no one person or disease is more important than the next.

[MHGinTN]

Thank you so much for the link.

In light of the following from the source you gave, what are we to make of 'how the RNAi is derived?'... They first showed that siRNAs are produced even in the absence of RNAi using Drosophila embryo extract.

[VetoBill]

I know there are some legitimate clinical trials needed, but often it seems the FDA is so afraid a drug/medical method is going to kill someone they would rather let those people die.

[Doc On The Bay]

no--- god will merely wonder "what took us so long!"

[Bad~Rodeo]

You're going to make me work at this aren't you...L~

Ok, here's the way i understand it, excerpt from, never mind...

Double-stranded RNA (dsRNA) is a potent and specific inhibitor (RNAi) of gene activity in Drosophila. dsRNA corresponding to a single gene specifically interferes with expression of that gene by causing rapid degradation of the cytoplasmic mRNA product. A concentration of dsRNA that is an order-of-magnitude lower than the level of mRNA transcripts is sufficient to degrade most transcripts. Interference of gene expression can persist for at least fourteen days in an organism during which the body size increases 100-fold. These latter two properties indicate that the RNAi effect is amplified and highly stable. However, we find that RNAi is efficiently initiated only in the germline or early blastoderm-stage,suggesting that its normal function is limited to those stages. In order to understand the mechanism behind RNAi, we have undertaken a genetic screen for mutants that are resistant to RNAi. Results from the screen will be presented. In parallel, we are using a cell-free system derived from syncitial blastoderm extracts that mimics RNAi in vivo. Evidence from this in vitro system and from embryo experiments rule out RNA-directed RNA synthesis as a possible step in the RNAi process. This result is in contradiction to evidence that a similar phenomenon in plants and fungi use RNA synthesis.

[glory]

You said it. Incredible!

[cactusSharp]

guess he hide eye glasses too huh ?
God din;y hide it....he allowed it
via free will

[chachacha]

Any practicing gay person should not recieve one penny's worth of cure till all those who "you refered to" and "I refered to", who got it through a secondary method.

NO cure for the practicing Gay's till all the others get it. PERIOD. GET IT TIGHTEN?

I think I referred to the left gay community in my post. I stand on my statement.

Maybe you read to fast.

[Chemist_Geek]

Yeah, but OTOH, patients used to be sold snake oil and dropped dead more from the "med" than the illness...

[chachacha]

I understand this and I'm not refering to them. I'm refering to the practicing gay's. I stand on my statement and I'm proud of it.

[realpatriot71]

You'll have to forgive my laziness, but I'm in the middle of sectional exams. What is the method of getting the specific RNAi to the specific target cells. Retrovirus?

[reformedliberal]

Drosophilia are fruitflies.

[realpatriot71]

You're right about the FDA being a "pain in the ass," but you wouldn't want physicians and scientists injecting anything and everything into a person before research is done. What kills one bad thing, usually kills another good thing as well.

For instance (if you already know this - forgive me) about 2 years ago during retroviral gene therapy trials a young man suddenly died. I personally think that stopping all such trials was a mistake, but care needs to be taken. Don't you think?

[chachacha]

What is wrong? If you are gay and you got aids because of your "alternative life style" you are not deserving of the cure till all those who are not gay get their cure.

[Hostage]

There have been many tantalizingly effective anti-cancer drugs that work only in a petri dish. The real problem is how to deliver these agents to where they can be effective.

Let's pray this is one that succeeds.

[Bad~Rodeo]

go study, .....post me tomorrow...S~

[Dinsdale]

So, why did God hide it?

For the same reason she created billion+ year old photons from distant stars a mear few thousand light years from the earth.

She's got a great, though clearly dark, sense of humor.

[HiTech RedNeck]

Same ol' lame ol'.

[Mike Darancette]

Curing cancer will drive up the Alzheimers rate.